1-(2-氯乙基)哌啶盐酸盐合成路线

3040-44-6N-羟乙基哌啶→2008-75-51-(2-氯乙基)哌啶盐酸盐

参考文献

Neurochem (International) Limited
Patent: US2006/223855 A1, 2006 ;
Location in patent: Page/Page column 160-161 ;

110-89-4哌啶+107-07-32-氯乙醇→2008-75-51-(2-氯乙基)哌啶盐酸盐

参考文献

CHINA PHARMACEUTICAL UNIVERSITY; Xiang, Hua; Wang, Tianlin; Xiao, Hong; You, Qidong; Yao, Yao; Li, Xiaobo; Liao, Qingjiang
Patent: US2013/85140 A1, 2013 ;
Location in patent: Paragraph 0052; 0053 ;

540-38-54-碘苯酚+2008-75-51-(2-氯乙基)哌啶盐酸盐→103808-68-04-碘-[2-(1-哌啶基)乙氧基l]苯

参考文献

Li, Xun; Reuman, Michael; Russell, Ronald K.; Adams, Richard; Ma, Robert; Beish, Sandra; Branum, Shawn; Youells, Scott; Roberts, Jerry; Jain, Nareshkumar; Kanojia, Ramesh; Sui, Zhihua
Organic Process Research and Development, 2007 , vol. 11, # 3 p. 414 - 421

→14256-74-7

参考文献

Bioorganic and Medicinal Chemistry, , vol. 10, # 8 p. 2535 - 2542

2008-75-51-(2-氯乙基)哌啶盐酸盐+99-93-4对羟基苯乙酮→2079-51-8

参考文献

Kumar, Atul; Tripathi, Vishwa Deepak; Kumar, Promod; Gupta, Lalit Prakash; Akanksha; Trivedi, Ritu; Bid, Hemant; Nayak; Siddiqui, Jawed A.; Chakravarti, Bandana; Saxena, Ruchi; Dwivedi, Anila; Siddiquee; Siddiqui; Konwar, Rituraj; Chattopadhyay, Naibedya
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 18 p. 5409 - 5419

2008-75-51-(2-氯乙基)哌啶盐酸盐→30419-75-1

参考文献

Ukhin, L.Yu.; Akopova; Bicherov; Kuzmina; Morkovnik; Borodkin
Tetrahedron Letters, 2011 , vol. 52, # 42 p. 5444 - 5447

106-41-24-溴苯酚+2008-75-51-(2-氯乙基)哌啶盐酸盐→836-58-81-(2-(4-溴苯氧基)乙基)哌啶

参考文献

Clegg, Nicola J.; Paruthiyil, Sreenivasan; Leitman, Dale C.; Scanlan, Thomas S.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 19 p. 5989 - 6003

93148-78-8+2008-75-51-(2-氯乙基)哌啶盐酸盐+99-76-3对羟基苯甲酸甲酯→84449-80-94-[2-哌啶-1-乙氧基]苯甲酸盐酸盐

参考文献

Eli Lilly and Company
Patent: US5631369 A1, 1997 ;

2008-75-51-(2-氯乙基)哌啶盐酸盐+99-76-3对羟基苯甲酸甲酯→89407-97-6+84449-80-94-[2-哌啶-1-乙氧基]苯甲酸盐酸盐

参考文献

Eli Lilly and Company
Patent: US5631369 A1, 1997 ;

2008-75-51-(2-氯乙基)哌啶盐酸盐+99-76-3对羟基苯甲酸甲酯→84449-80-94-[2-哌啶-1-乙氧基]苯甲酸盐酸盐

参考文献

Eli Lilly and Company
Patent: US5631369 A1, 1997 ;