2-羟甲基-5-甲氧基苯并咪唑合成路线 （共 5 条）
反应条件
hydrogenchloride in water 6 h; Reflux;
参考文献
Eom, Young Woo; Oh, Sangtae; Woo, Ho Bum; Ham, Jungyeob; Ahn, Chan Mug; Lee, Seokjoon
Bulletin of the Korean Chemical Society, 2013 , vol. 34, # 4 p. 1272 - 1274
反应条件
thionyl chloride in dichloromethane T=20°C; 2 h;
参考文献
PLEXXIKON, INC.
Patent: WO2008/80001 A2, 2008 ;
Location in patent: Page/Page column 110 ;
反应条件
1: With sodium hydroxide; potassium permanganate in water 1 h; Heating / reflux; 2: With acetic acid in water pH=4;
参考文献
Lane, Charlotte Alice Louise; Price, David Anthony
Patent: US2006/111416 A1, 2006 ;
Location in patent: Page/Page column 11 ;
US 20060111416 A1
反应条件
tetrabutylammomium bromide; potassium hydroxide in tetrahydrofuran
T=0°C;
参考文献
Eom, Young Woo; Oh, Sangtae; Woo, Ho Bum; Ham, Jungyeob; Ahn, Chan Mug; Lee, Seokjoon
Bulletin of the Korean Chemical Society, 2013 , vol. 34, # 4 p. 1272 - 1274
反应条件
1: tetrabutylammomium bromide; potassium hydroxide / tetrahydrofuran / 0 °C
2: Dess-Martin periodane / dichloromethane / 6 h / 0 °C
View Scheme
参考文献
Eom, Young Woo; Oh, Sangtae; Woo, Ho Bum; Ham, Jungyeob; Ahn, Chan Mug; Lee, Seokjoon
Bulletin of the Korean Chemical Society, 2013 , vol. 34, # 4 p. 1272 - 1274
