4'-甲氧基-2-硝基联苯合成路线 （共 37 条）
反应条件
1: 1-chloro-1-(4'-methoxyphenyl)silacyclobutane With tetrabutyl ammonium fluoride in tetrahydrofuran 2: 1-iodo-2-nitro-benzene With tri-tert-butyl phosphine; tetrabutyl ammonium fluoride; bis(η3-allyl-μ-chloropalladium(II)) in tetrahydrofuran 3 h; Heating; Further stages.;
参考文献
Denmark, Scott E.; Wu, Zhicai
Organic Letters, 1999 , vol. 1, # 9 p. 1495 - 1498
反应条件
dihydrogen peroxide; sodium carbonate; (Ph3P)4Pd in ethanol; dichloromethane; benzene
参考文献
BRISTOL-MYERS SQUIBB COMPANY
Patent: EP771791 A1, 1997 ;
EP 0771791 A1
反应条件
caesium carbonate; triphenylphosphine; palladium dichloride in N,N-dimethyl acetamide T=90°C; 2 h;
参考文献
Rao, Maddali L.N.; Jadhav, Deepak N.; Banerjee, Debasis
Tetrahedron, 2008 , vol. 64, # 24 p. 5762 - 5772
参考文献
The Boots Company
Patent: US5302720 A1, 1994 ;
反应条件
tetrakis(triphenylphosphine) palladium(0) in toluene Stille Cross Coupling; 24 h; Inert atmosphereReflux;
参考文献
Universiteit Antwerpen; Kuvshinov, Alexandr; Franck, Philippe; Depraetere, Stefaan; Maes, Bert
Patent: EP2662379 A1, 2013 ;
Location in patent: Paragraph 0103 ;
反应条件
PEG 4000; palladium diacetate; potassium carbonate T=120°C; 20 h;
参考文献
Wang, Liang; Zhang, Yuhong; Liu, Leifang; Wang, Yanguang
Journal of Organic Chemistry, 2006 , vol. 71, # 3 p. 1284 - 1287
反应条件
potassium phosphate; tetrakis(triphenylphosphine) palladium(0) in ethylene glycol dimethyl ether T=85°C; 2.5 h;
参考文献
Holzapfel, Cedric W.; Dwyer, Catherine
Heterocycles, 1998 , vol. 48, # 8 p. 1513 - 1518
反应条件
caesium carbonate; trimethylphosphane; tris(dibenzylideneacetone)dipalladium (0) in tetrahydrofuran; ethylene glycol dimethyl ether Suzuki reaction; 16 h; Heating;
参考文献
Widdowson, David A.; Wilhelm, Rene
Chemical Communications, 2003 , # 5 p. 578 - 579
反应条件
C43H54N2S; palladium diacetate; potassium carbonate in water; isopropyl alcohol T=100°C; Suzuki-Miyaura coupling reaction; 6 h; Aerobic conditionSealed tube;
参考文献
Li, Hong-Ling; Wu, Zhi-Sheng; Yang, Min; Qi, Yan-Xing
Catalysis Letters, 2010 , vol. 137, # 1-2 p. 69 - 73
反应条件
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride in toluene Suzuki-Miyaura reaction; 24 h; Heating;
参考文献
Cammidge, Andrew N.; Goddard, Victoria H. M.; Gopee, Hemant; Harrison, Nicola L.; Hughes, David L.; Schubert, Christopher J.; Sutton, Benjamin M.; Watts, Gary L.; Whitehead, Andrew J.
Organic Letters, 2006 , vol. 8, # 18 p. 4071 - 4074
