2-氨基-3-氰基-5-甲基吡嗪 1-氧化物合成路线 （共 4 条）
反应条件
1: With hydrogen; acetic acid; platinum on carbon in methanol P=3102.97 Torr; 18 h; Darco KB-B; 2: With sodium hydroxide in methanol; water
参考文献
ICOS CORPORATION
Patent: WO2006/105262 A1, 2006 ;
Location in patent: Page/Page column 65 ;
反应条件
in isopropyl alcohol
T=20°C; 18 h;
参考文献
ICOS CORPORATION
Patent: WO2006/105262 A1, 2006 ;
Location in patent: Page/Page column 65 ;
反应条件
lithium iodide in pyridine; water
2 h; Heating;
参考文献
Taylor, Edward C.; Dumas, Donald J.
Journal of Organic Chemistry, 1980 , vol. 45, # 12 p. 2485 - 2489
反应条件
trichlorophosphate in N,N-dimethyl-formamide
T=0 - 80°C; 2 h;
参考文献
Ioannidis, Stephanos; Lamb, Michelle L.; Davies, Audrey M.; Almeida, Lynsie; Su, Mei; Bebernitz, Geraldine; Ye, Minwei; Bell, Kirsten; Alimzhanov, Marat; Zinda, Michael
Bioorganic and Medicinal Chemistry Letters, 2009 , vol. 19, # 23 p. 6524 - 6528
