6-硝基-1H-1lambda~6~-苯并[b]噻吩-1,1-二酮合成路线 （共 10 条）
反应条件
nitric acid in sulfuric acid T=0°C; 0.5 h;
参考文献
WO2006/36024 A1, ;
Page/Page column 154-155 ;
反应条件
sulfuric acid; sodium nitrite Behandeln der Reaktionsloesung mit Hypophosphorigsaeure und wenig Kupfer(II)-sulfat;
参考文献
Journal of the American Chemical Society, , vol. 77, p. 5939,5943
反应条件
1: nitric acid 2: acetic acid; concentrated aqueous hydrochloric acid 3: sulfuric acid; sodium nitrite / Behandeln der Reaktionsloesung mit Hypophosphorigsaeure und wenig Kupfer(II)-sulfat View Scheme
参考文献
Journal of the American Chemical Society, , vol. 77, p. 5939,5943
反应条件
1: acetic acid; concentrated aqueous hydrochloric acid 2: sulfuric acid; sodium nitrite / Behandeln der Reaktionsloesung mit Hypophosphorigsaeure und wenig Kupfer(II)-sulfat View Scheme
参考文献
Journal of the American Chemical Society, , vol. 77, p. 5939,5943
反应条件
2: nitric acid 3: acetic acid; concentrated aqueous hydrochloric acid 4: sulfuric acid; sodium nitrite / Behandeln der Reaktionsloesung mit Hypophosphorigsaeure und wenig Kupfer(II)-sulfat View Scheme
参考文献
Journal of the American Chemical Society, , vol. 77, p. 5939,5943
反应条件
1: acetic acid; aq. H2O2 / 0.5 h / Heating 2: nitric acid View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 12, # 5 p. 963 - 968
参考文献
Journal of the Chemical Society, , p. 1615,1617
反应条件
hydrogen; palladium on activated charcoal in 2-methoxy-ethanol T=50°C; P=2625.2 Torr; 4 h;
参考文献
Sauter; Jordis; Tanyolac; Martinek
Archiv der Pharmazie, 1988 , vol. 321, # 4 p. 241 - 246
反应条件
iron; ammonium chloride in ethanol; water
参考文献
Villar; Encio; Migliaccio; Gil; Martinez-Merino
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 5 p. 963 - 968
反应条件
1: 81 percent / H2 / Pd/C / 2-methoxy-ethanol / 4 h / 50 °C / 2625.2 Torr
2: 67 percent / DIBAL / hexane; dioxane / 5 h / 70 °C
View Scheme
参考文献
Sauter; Jordis; Tanyolac; Martinek
Archiv der Pharmazie, 1988 , vol. 321, # 4 p. 241 - 246
