1-(三甲基硅氧基)环戊烯合成路线 （共 155 条）
反应条件
1: tetra-n-butylammonium fluoride (TBAF) / tetrahydrofuran / 16 h / Ambient temperature
2: K2CO3, KOAc / Pd(OAc)2 / tetrahydrofuran; dimethylformamide / 6 h / 80 °C
View Scheme
参考文献
Webel, Matthias; Reissig, Hans-Ulrich
Synlett, 1997 , vol. 1997, # 10 p. 1141 - 1142
反应条件
1: 35 percent / SnCl4 / CH2Cl2 / 2 h / -20 °C
2: 6 percent / Ra-Ni / ethanol / 70 deg C, 4 h, rt, 20 h
View Scheme
参考文献
Pohmakotr, Manat; Thisayukta, Jirakorn
Tetrahedron Letters, 1997 , vol. 38, # 38 p. 6759 - 6762
反应条件
Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Prieto, J. Antonio; Larson, Gerald L.
Synthetic Communications, 1980 , vol. 10, # 9 p. 675 - 684
反应条件
1: With triethylamine in hexane
T=20°C; Inert atmosphere;
2: With toluene-4-sulfonic acid in hexane
T=70°C; Inert atmosphere; regioselective reaction;
参考文献
Schmitt, Daniel C.; Lam, Leighann; Johnson, Jeffrey S.
Organic Letters, 2011 , vol. 13, # 19 p. 5136 - 5139
反应条件
hydrogenchloride; zinc(II) chloride
1.) ethyl acetate, room temp.; Yield given. Multistep reaction;
参考文献
Makin, S. M.; Kruglikova, R. I.; Tagirov, T. K.; Kharitonova, O. V.
Journal of Organic Chemistry USSR (English Translation), 1984 , vol. 20, # 6 p. 1075 - 1078
Zhurnal Organicheskoi Khimii, 1984 , vol. 20, # 6 p. 1182 - 1185
反应条件
zinc(II) chloride in ethyl acetate
Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Makin, S. M.; Kruglikova, R. I.; Tagirov, T. K.; Kharitonova, O. V.
Journal of Organic Chemistry USSR (English Translation), 1984 , vol. 20, # 6 p. 1075 - 1078
Zhurnal Organicheskoi Khimii, 1984 , vol. 20, # 6 p. 1182 - 1185
反应条件
titanium tetrachloride in dichloromethane
T=-78°C; Alkylation;
参考文献
Lalic, Gojko; Petrovski, Zeljko; Galonic, Danica; Matovic, Radomir; Saicic, Radomir N
Tetrahedron, 2001 , vol. 57, # 3 p. 583 - 591
反应条件
Nafion-TMS in dichloromethane
T=-78 - 20°C; 40 h;
参考文献
Haunert, Frank; Bolli, Martin H.; Hinzen, Berthold; Ley, Steven V.
Journal of the Chemical Society - Perkin Transactions 1, 1998 , # 15 p. 2235 - 2237
反应条件
1: With sodium dithionite; sodium hydrogencarbonate in acetonitrile
4 h;
2: With triethylamine in diethyl ether
24 h;
参考文献
Dmowski, Wojciech; Ignatowska, Jolanta
Journal of Fluorine Chemistry, 2003 , vol. 123, # 1 p. 37 - 42
反应条件
trimethylsilyl iodide in dichloromethane
T=-78°C; 1 h;
参考文献
Sakurai, Hideki; Sasaki, Koshi; Hosomi, Akira
Bulletin of the Chemical Society of Japan, 1983 , vol. 56, # 10 p. 3195 - 3196
