1-(1-溴乙基)-4-硝基苯合成路线 （共 23 条）
反应条件
N-bromosuccinmide; dibenzoyl peroxide in tetrachloromethane 1.5 h; Heating / reflux;
参考文献
PFIZER PRODUCTS INC.
Patent: WO2008/23235 A1, 2008 ;
Location in patent: Page/Page column 57 ;
反应条件
Sodium bromate; sodium hydrogensulfite in water; ethyl acetate T=20°C; Bromination; 7 h;
参考文献
Kikuchi, Daisuke; Sakaguchi, Satoshi; Ishii, Yasutaka
Journal of Organic Chemistry, 1998 , vol. 63, # 17 p. 6023 - 6026
反应条件
dibenzoyl peroxide in tetrachloromethane 1 h; Heating / reflux;
参考文献
VERTEX PHARMACEUTICALS INCORPORATED
Patent: WO2004/46120 A2, 2004 ;
Location in patent: Page 173;174 ;
WO 2004/046120 A2
反应条件
hydrogenchloride; phosphorus tribromide; sodium borohydride in ethanol; dichloromethane
参考文献
Mitsui Toatsu Chemicals, Incorporated
Patent: US5308848 A1, 1994 ;
反应条件
Oxonereg;; potassium bromide in dichloromethane; water T=20°C; 3 h; visible light irradiation;
参考文献
Moriyama, Katsuhiko; Takemura, Misato; Togo, Hideo
Organic Letters, 2012 , vol. 14, # 9 p. 2414 - 2417
反应条件
in dichloromethane; carbon tetrabromide
参考文献
Wendstone Chemicals PLC
Patent: US5164515 A1, 1992 ;
反应条件
tetrabutylammomium bromide in acetonitrile T=30 - 55°C; other solvent; in the presence or in the absence of lutidine; at different bromide ion concentration; KineticsProduct distributionMechanism;
参考文献
Stein, Allan R.
Canadian Journal of Chemistry, 1987 , vol. 65, p. 363 - 371
反应条件
tetrabutylammomium bromide in acetonitrile T=30 - 55°C; other solvent; in the presence or in the absence of lutidine; at different bromide ion concentration; KineticsProduct distributionMechanism;
参考文献
Stein, Allan R.
Canadian Journal of Chemistry, 1987 , vol. 65, p. 363 - 371
反应条件
Oxonereg; in water; acetonitrile T=20°C; 5.5 h;
参考文献
Tetrahedron, , vol. 68, # 47 p. 9763 - 9768,6
Tetrahedron, , vol. 68, # 47 p. 9763 - 9768
反应条件
KNO2; 2,2,6,6-tetramethyl-1-piperidinyloxy, free radical; oxygen in water 12 h; Reflux;
参考文献
Liu, Qifa; Lu, Ming; Yang, Fei; Wei, Wei; Sun, Feng; Yang, Zhenbang; Huang, Sufeng
Synthetic Communications, 2010 , vol. 40, # 8 p. 1106 - 1114
