4-氯-alpha,alpha-二甲基苄醇合成路线 （共 26 条）
反应条件
strontium in tetrahydrofuran T=20°C; Barbier reaction; 0.5 h;
参考文献
Miyoshi, Norikazu; Matsuo, Tsuyoshi; Wada, Makoto
European Journal of Organic Chemistry, 2005 , # 20 p. 4253 - 4255
反应条件
1: methyllithium With iron(III) chloride in diethyl ether cooling; 2: 4-chloro-benzoyl chloride in tetrahydrofuran T=-40°C;
参考文献
Fuerstner, Alois; Krause, Helga; Lehmann, Christian W.
Angewandte Chemie - International Edition, 2006 , vol. 45, # 3 p. 440 - 444
参考文献
Sato, Kazuo; Honma, Toyokuni; Sugai, Soji
Agricultural and Biological Chemistry, 1985 , vol. 49, # 12 p. 3563 - 3568
反应条件
in diethyl ether T=0°C; 3 h;
参考文献
Reetz, M. T.; Kyung, S. H.; Huellmann, M.
Tetrahedron, 1986 , vol. 42, # 11 p. 2931 - 2935
反应条件
in α,α,α-trifluorotoluene T=25°C; Photolysis; optical yield given as percent dediastereoselective reaction;
参考文献
Schur, Christine; Becker, Nina; Bergstraesser, Uwe; Gottwald, Thomas; Hartung, Jens
Tetrahedron, 2011 , vol. 67, # 12 p. 2338 - 2347
参考文献
Brown et al.
Journal of the American Chemical Society, 1957 , vol. 79, p. 1906,1909
反应条件
1: 2-chloro-5-carboxybenzene With sodium hydride in tetrahydrofuran T=20°C; 0.5 h; 2: methyl iodide With strontium in tetrahydrofuran T=20°C; 0.75 h;
参考文献
Miyoshi, Norikazu; Matsuo, Tsuyoshi; Asaoka, Masashi; Matsui, Aki; Wada, Makoto
Chemistry Letters, 2007 , vol. 36, # 1 p. 28 - 29
反应条件
1: methyl bromide With magnesium in diethyl ether 2: para-chloroacetophenone in diethyl ether T=20°C; Grignard reaction; 6 h; Further stages.;
参考文献
Zagozda, Marcin; Plenkiewicz, Jan
Tetrahedron Asymmetry, 2007 , vol. 18, # 12 p. 1457 - 1464
反应条件
sulfuric acid T=25°C; Rate constantEquilibrium constant;
参考文献
Pytela, Oldrich; Trlida, Bronislav
Collection of Czechoslovak Chemical Communications, 2007 , vol. 72, # 8 p. 1025 - 1036
参考文献
Baciocchi, Enrico; Bietti, Massimo; Salamone, Michela; Steenken, Steen
Journal of Organic Chemistry, 2002 , vol. 67, # 7 p. 2266 - 2270
