反应条件
1: 1.) LDA / 1.) THF, hexane, -60 deg C, 10 min, 2.) THF, hexane, -60 deg C, 30 min
2: 1.) NaH / 1.) Et2O, reflux, 2.5 h, 2.) Et2O, reflux, 4 h
3: 5percent aq. NaOH / ethanol / 7 h / Ambient temperature
View Scheme
参考文献
Smith; Blackwell; Demaine; Garland; Hodson; Hyde; Parke; Rose; Sawyer; Tilling
European Journal of Medicinal Chemistry, 1996 , vol. 31, # 5 p. 347 - 358
