反应条件
1: pyrazinecarbonitrile With trifluoroacetic acid in dichloromethane; water
0.25 h;
2: 3,4,5-trimethoxyphenylboronic acid With iron sulphate heptahydrate; dipotassium peroxodisulfate in dichloromethane; water
T=20°C; 5 h;
3: With sodium hydroxide in dichloromethane; water
T=20°C; Overall yield = 84 percent;
参考文献
Komeyama, Kimihiro; Nagao, Yuya; Abe, Manabu; Takaki, Ken
Bulletin of the Chemical Society of Japan, 2014 , vol. 87, # 2 p. 301 - 313
