9H-吡啶并[3,4-b]吲哚-1-醇合成路线 （共 5 条）
反应条件
phosphorus oxytribromide in various solvent(s) T=120°C; 4 h;
参考文献
Bracher, Franz; Hildebrand, Dirk
Tetrahedron, 1994 , vol. 50, # 43 p. 12329 - 12336
反应条件
1: 88 percent / POBr3 / various solvent(s) / 4 h / 120 °C 2: potassium hydride (35 percent in oil), tert.-BuLi / tetrahydrofuran / 1 h / -78 - 0 °C 3: 51 percent / tetrahydrofuran / 4 h / -78 °C View Scheme
参考文献
Bracher, Franz; Hildebrand, Dirk
Tetrahedron, 1994 , vol. 50, # 43 p. 12329 - 12336
反应条件
1: 70 percent / POCl3, PhNMe2 / 24 h / Heating
2: 87 percent / Na2CO3*10H2O / Pd(Ph3P)4 / toluene; H2O; ethanol / 17 h / Heating
View Scheme
参考文献
Bracher, Franz; Hildebrand, Dirk
Liebigs Annalen der Chemie, 1992 , # 12 p. 1315 - 1320
反应条件
1: 55 percent / pyridine / 7 h / Ambient temperature
2: 71 percent / LiCl / Pd(PPh3)4, 18-crown-6 / toluene / 7 h / Heating
View Scheme
参考文献
Bracher; Hildebrand; Ernst
Archiv der Pharmazie, 1994 , vol. 327, # 2 p. 121 - 122
反应条件
1: 88 percent / POBr3 / various solvent(s) / 4 h / 120 °C
2: potassium hydride (35 percent in oil), tert.-BuLi / tetrahydrofuran / 1 h / -78 - 0 °C
3: 53 percent / ZnCl2, Pd(Ph3P)4 / tetrahydrofuran / 22 h / Heating
View Scheme
参考文献
Bracher, Franz; Hildebrand, Dirk
Tetrahedron, 1994 , vol. 50, # 43 p. 12329 - 12336
