(3,5-二甲基-4-异恶唑基)甲醇合成路线 （共 14 条）
反应条件
potassium dichromate; sulfuric acid
参考文献
Kotschetkow et al.
Zhurnal Obshchei Khimii, 1958 , vol. 28, p. 2736,2743; engl. Ausg. S. 2762, 2768
反应条件
1: 90 percent / BaMnO4 / benzene / 3 h / Heating
2: 78 percent / aq. NH4OH / ethanol / 20 h / Heating
View Scheme
参考文献
Natale, Nicholas R.; Quincy, David A.
Synthetic Communications, 1983 , vol. 13, # 10 p. 817 - 822
反应条件
(i) nBuLi, THF, hexane, (ii) /BRN= 969135/; Multistep reaction;
参考文献
Gainer,J. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1976 , p. 994 - 997
反应条件
phosphorus tribromide in dichloromethane
T=20°C; 3 h;
参考文献
CHLORION PHARMA, INC.; UNIVERSITE LAVAL; ATTARDO, Giorgio; TRIPATHY, Sasmita
Patent: WO2010/132999 A1, 2010 ;
Location in patent: Page/Page column 109 ;
