3-乙基-3-甲基-2-戊酮合成路线 （共 28 条）
参考文献
Nybergh
Chemische Berichte, 1922 , vol. 55, p. 1962
参考文献
Nybergh
Chemische Berichte, 1922 , vol. 55, p. 1962
反应条件
hydrogen; palladium-copper; silica gel in ethanol
T=25°C; P=760 Torr; Kinetics;
参考文献
Spee; Boersma; Meijer; Slagt; Van Koten; Geus
Journal of Organic Chemistry, 2001 , vol. 66, # 5 p. 1647 - 1656
反应条件
sulfuric acid
T=-10°C;
参考文献
Reeve; Karickhoff
Journal of the American Chemical Society, 1956 , vol. 78, p. 6053
反应条件
copper(l) chloride in diethyl ether
参考文献
Bauer,P.; Dubois,J.E.
Journal of the American Chemical Society, 1976 , vol. 98, # 22 p. 6999 - 7007
反应条件
1: thionyl chloride
View Scheme
参考文献
Whitmore; Lewis
Journal of the American Chemical Society, 1942 , vol. 64, p. 2965
Journal of the American Chemical Society, 1946 , vol. 68, p. 2751
反应条件
sulfuric acid
T=95 - 150°C;
参考文献
Kuwata
Nippon Kagaku Kaishi, 1941 , vol. 62, p. 1035,1037,1040
Chem.Abstr., 1947 , p. 3051
反应条件
1: 1.) iPr2NLi, HMPT; 2.) 10percent HCl / 1.) ether+THF, -60 deg C, 30 min 2.) r.t.
2: 63 percent / aq. NaOH solution / methanol / 18 h / Heating
3: 65 percent / Ambient temperature
View Scheme
参考文献
Chuit, C.; Foulon, J. P.; Normant, J. F.
Tetrahedron, 1980 , vol. 36, # 91 p. 2305 - 2310
反应条件
1: 63 percent / aq. NaOH solution / methanol / 18 h / Heating
2: 65 percent / Ambient temperature
View Scheme
参考文献
Chuit, C.; Foulon, J. P.; Normant, J. F.
Tetrahedron, 1980 , vol. 36, # 91 p. 2305 - 2310
反应条件
sulfuric acid
T=-40 - -10°C; 2 h; other reagents, solvents, times and temperatures; Product distribution;
参考文献
Martinelli, Michael J.; Khau, Vien V.; Horcher, Linus M.
Journal of Organic Chemistry, 1993 , vol. 58, # 20 p. 5546 - 5547
