3-(2-羟基乙基)-alpha-皮考啉合成路线 （共 9 条）
参考文献
Wilson; Harris
Journal of the American Chemical Society, 1949 , vol. 71, p. 2231
反应条件
diisobutylaluminium hydride in dichloromethane
T=-78 - 20°C; 3 h;
参考文献
Chen, Liuhong; Cressina, Elena; Dixon, Neil; Erixon, Karl; Agyei-Owusu, Kwasi; Micklefield, Jason; Smith, Alison G.; Abell, Chris; Leeper, Finian J.
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 30 p. 5924 - 5931
反应条件
1: sulfur; dioxane; aqueous <NH4>2S / 175 - 180 °C
2: P2O5
3: platinum; H2O / Hydrogenation
4: aqueous sulfuric acid; aqueous sodium nitrite
View Scheme
参考文献
Dornow; Schacht
Chemische Berichte, 1949 , vol. 82, p. 117,119
反应条件
1: tetrahydrofuran / -78 - 20 °C
2: sulfur / dichloromethane / 14 h / 120 °C
3: sulfuric acid / 16 h / Reflux
4: diisobutylaluminium hydride / dichloromethane / 3 h / -78 - 20 °C
View Scheme
参考文献
Chen, Liuhong; Cressina, Elena; Dixon, Neil; Erixon, Karl; Agyei-Owusu, Kwasi; Micklefield, Jason; Smith, Alison G.; Abell, Chris; Leeper, Finian J.
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 30 p. 5924 - 5931
反应条件
1: methanol. NaOH-solution; Raney nickel / Hydrogenation
2: aqueous hydrobromic acid / Erhitzen des Reaktionsprodukts mit Natriumacetat in Essigsaeure
3: ethanol; KOH-solution
View Scheme
参考文献
Raffauf
Helvetica Chimica Acta, 1950 , vol. 33, p. 102,106
反应条件
sulfuric acid; sodium nitrite
参考文献
Dornow; Schacht
Chemische Berichte, 1949 , vol. 82, p. 117,119
反应条件
1: platinum; H2O / Hydrogenation
2: aqueous sulfuric acid; aqueous sodium nitrite
View Scheme
参考文献
Dornow; Schacht
Chemische Berichte, 1949 , vol. 82, p. 117,119
反应条件
1: 100 - 110 °C / reagiert analog mit 3-Aethoxy-crotonaldehyd-diaethylacetal
2: sulfur; dioxane; aqueous <NH4>2S / 175 - 180 °C
3: P2O5
4: platinum; H2O / Hydrogenation
5: aqueous sulfuric acid; aqueous sodium nitrite
View Scheme
参考文献
Dornow; Schacht
Chemische Berichte, 1949 , vol. 82, p. 117,119
反应条件
1: P2O5
2: platinum; H2O / Hydrogenation
3: aqueous sulfuric acid; aqueous sodium nitrite
View Scheme
参考文献
Dornow; Schacht
Chemische Berichte, 1949 , vol. 82, p. 117,119
