1-苄基-1,2,3,4-四氢异喹啉合成路线 (共 40 条)
反应条件
1: P2O5 / toluene / Heating 2: NaBH4; EtOH / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 10, # 15 p. 1669 - 1671
反应条件
para-dicyanobenzene in water; acetonitrile Irradiation;
参考文献
Lewis, Frederick D.; Bassani, Dario M.; Burch, Eric L.; Cohen, Bliss E.; Engleman, Jeffrey A.; Reddy, G. Dasharatha; Schneider, Siegfried; Jaeger, Wighard; Gedeck, Peter; Gahr, Michael
Journal of the American Chemical Society, 1995 , vol. 117, # 2 p. 660 - 669
参考文献
Acta Phytochimica, , vol. 3, p. 253
Chem. Zentralbl., , vol. 98, # II p. 1966
Journal of the Chemical Society, , p. 2270
反应条件
1: benzyl chloride With iodine; magnesium; ethylene dibromide in tetrahydrofuran T=-10°C; Grignard reaction; 1 h; 2: 3,4-dihydro-isoquinoline in tetrahydrofuran T=-78 - 20°C;
参考文献
Al-Hiari, Yusuf M.; Bennett, Stephen J.; Cox, Brian; Davies, Robert J.; Khalaf, Abedawn I.; Waigh, Roger D.; Worsley, Alan J.
Journal of Heterocyclic Chemistry, 2005 , vol. 42, # 4 p. 647 - 659
反应条件
rhenium heptasulfide; hydrogen in benzene T=250°C; P=106400 Torr; 4 h;
参考文献
Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), , vol. 40, # 6.2 p. 1253 - 1256
Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, , # 6 p. 1413 - 1416
反应条件
boron trifluoride diethyl etherate; sec.-butyllithium in tetrahydrofuran T=-78 - 0°C; 1 h;
参考文献
Kessar, S. V.; Singh, Paramjit; Singh, Kamal Nain; Kaul, Vijay K.; Kumar, Gurdeep
Tetrahedron Letters, 1995 , vol. 36, # 46 p. 8481 - 8484
反应条件
titanium(III) chloride in methanol Ambient temperature;
参考文献
Murahashi, Shun-Ichi; Kodera, Yoichi
Tetrahedron Letters, 1985 , vol. 26, # 38 p. 4633 - 4636
反应条件
trifluoroacetic acid in dichloromethane 2 h; Ambient temperature;
参考文献
Coppola
Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 7 p. 1769 - 1772
反应条件
3-cyanobenzylnitrile in water; acetonitrile Irradiation;
参考文献
Lewis; Reddy
Tetrahedron Letters, 1992 , vol. 33, # 30 p. 4249 - 4252
反应条件
hydrogenchloride in ethanol 30 h; Heating;
参考文献
Shinohara, Tatsumi; Takeda, Akira; Toda, Jun; Terasawa, Noriyo; Sano, Takehiro
Heterocycles, 1997 , vol. 46, # 1 p. 555 - 565