1,2,3-三甲基-1H-吲哚合成路线 （共 30 条）
反应条件
1,4-diaza-bicyclo[2.2.2]octane; dimethylsulfide; oxygen in dimethyl sulfoxide T=100°C; P=760.051 Torr; 4 h; chemoselective reaction;
参考文献
Wang, Yi-Feng; Zhang, Feng-Lian; Chiba, Shunsuke
Synthesis, 2012 , vol. 44, # 10 p. 1526 - 1534
参考文献
Ciamician; Boeris
Gazzetta Chimica Italiana, 1894 , vol. 24 II, p. 301
Gazzetta Chimica Italiana, 1897 , vol. 27 I, p. 78
参考文献
Ciamician; Boeris
Gazzetta Chimica Italiana, 1894 , vol. 24 II, p. 301
Gazzetta Chimica Italiana, 1897 , vol. 27 I, p. 78
反应条件
tributyl-amine in N,N-dimethyl-formamide
T=285°C; P=112511 Torr; 0.05 h;
参考文献
Glasnov, Toma N.; Kappe, C. Oliver; Holbrey, John D.; Seddon, Kenneth R.; Yan, Ting
Green Chemistry, 2012 , vol. 14, # 11 p. 3071 - 3076,6
反应条件
1: 2,3-dimethyl-indole With sodium hydride in tetrahydrofuran
T=80°C; 2 h;
2: methyl iodide in tetrahydrofuran
T=80°C; 1 h;
参考文献
Douglas, Nicholas; Neef, Charles J.; Rogers, Robert A.; Stanley, Jake A.; Armitage, Jacob; Martin, Ben; Hudnall, Todd W.; Brittain, William J.
Journal of Physical Organic Chemistry, 2013 , vol. 26, # 8 p. 688 - 695
反应条件
tris(triphenylphosphine)ruthenium(II) chloride in 1,4-dioxane
T=180°C; 20 h;
参考文献
Tsuji, Yasushi; Huh, Keun-Tae; Watanabe, Yoshihisa
Journal of Organic Chemistry, 1987 , vol. 52, # 9 p. 1673 - 1680
反应条件
(E,Z)-crotononitrile; tri-ruthenium(0)dodecacarbonyl; BIPHEP; zinc(II) chloride in 1,1-dimethylpropan-1-ol
T=130°C; Fischer Indole Synthesis; 3 h; Inert atmosphereMicrowave irradiation;
参考文献
Porcheddu, Andrea; Mura, Manuel G.; De Luca, Lidia; Pizzetti, Marianna; Taddei, Maurizio
Organic Letters, 2012 , vol. 14, # 23 p. 6112 - 6115
反应条件
tetrabutyl-ammonium chloride; potassium carbonate; palladium dichloride in N,N-dimethyl acetamide
T=100°C; 20 h;
参考文献
Liu, Yan; Yao, Bo; Deng, Chen-Liang; Tang, Ri-Yuan; Zhang, Xing-Guo; Li, Jin-Heng
Organic Letters, 2011 , vol. 13, # 5 p. 1126 - 1129
反应条件
in N,N-dimethyl-formamide
T=80°C;
参考文献
Suvorov, N. N.; Plutitskii, D. N.; Smushkevich, Yu. I.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1981 , vol. 17, # 3 p. 268 - 270
Khimiya Geterotsiklicheskikh Soedinenii, 1981 , vol. 17, # 3 p. 365 - 367
参考文献
Fitzpatrick; Hiser
Journal of Organic Chemistry, 1957 , vol. 22, p. 1703
