反应条件
1.1: sulfuric acid / N,N-dimethyl-formamide / 20 °C 2.1: sodium hydride / N,N-dimethyl-formamide 2.2: 4 h / 20 °C 3.1: hydrogenchloride; water / methanol / 4 h / 20 °C 4.1: sodium periodate / ethanol; water; methanol / 3 h / 20 °C 5.1: copper(II) bis(trifluoromethanesulfonate); borane-THF / 2 h / 20 °C / |Inert atmosphere 6.1: 1H-imidazole; 4-(N,N-dimethlyamino)pyridine / dichloromethane / 24 h / 20 °C / |Inert atmosphere 7.1: pyridine / dichloromethane / 1 h / -15 °C / |Inert atmosphere 8.1: sodium azide / N,N-dimethyl-formamide / 2 h / 20 °C 9.1: triphenylphosphine / tetrahydrofuran / 4 h / 20 °C 9.2: 4 h / 20 °C 10.1: pyridine / 2 h / 0 - 20 °C 11.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 4 h / 20 °C / |Inert atmosphere 12.1: dimethyl sulfoxide; oxalyl dichloride / dichloromethane / 1 h / -78 °C / |Inert atmosphere 12.2: 0.75 h / -78 - 20 °C / |Inert atmosphere 13.1: titanium tetrachloride / dichloromethane / 0.25 h / 0 °C / |Inert atmosphere 13.2: 2 h / 0 °C / |Inert atmosphere 14.1: 10 Pd/C; hydrogen / ethanol / 96 h / 20 °C 15.1: sodium hydride / tetrahydrofuran / 1 h / 0 °C / |Inert atmosphere 16.1: triethylamine / dichloromethane / 0.75 h / 0 °C 17.1: sodium azide / ethanol; water / 8 h / |Reflux 18.1: triphenylphosphine / tetrahydrofuran / 4 h / 20 °C 18.2: Staudinger Azide Reduction / 24 h / 20 °C View Scheme
参考文献
Tetrahedron Letters, , vol. 53, # 46 p. 6209 - 6211,3
