2-[(4-硝基苯基)氨基]乙醇合成路线 （共 28 条）
反应条件
sodium hydroxide in water; acetonitrile
T=60°C; 3 h; Yield given;
参考文献
Knipe, Anthony C.; Lound-Keast, Joseph; Sridhar, Narayan
Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999), 1984 , p. 1885 - 1892
参考文献
Artico,M. et al.
Farmaco, Edizione Scientifica, 1969 , vol. 24, p. 179 - 190
反应条件
sodium carbonate
T=0 - 18°C; 1.5 h; Irradiationother β-(nitrophenoxy)ethylamines; Product distributionMechanism;
参考文献
Wubbels, Gene G.; Halverson, Ann M.; Oxman, Joe D.; Bruyn, Van H. De
Journal of Organic Chemistry, 1985 , vol. 50, # 23 p. 4499 - 4504
参考文献
Kremer
Journal of the American Chemical Society, 1937 , vol. 59, p. 1681
Journal of the American Chemical Society, 1939 , vol. 61, p. 1321,1323
反应条件
1: TEA / CH2Cl2 / 0.5 h / 0 - 20 °C
2: 86 percent / TEA; DBU / CH2Cl2 / 70 h
View Scheme
参考文献
Hoeglund, Iisa P. J.; Silver, Satu; Engstroem, Mia T.; Salo, Harri; Tauber, Andrei; Kyyroenen, Hanna-Kaisa; Saarenketo, Pauli; Hoffren, Anna-Marja; Kokko, Kurt; Pohjanoksa, Katariina; Sallinen, Jukka; Savola, Juha-Matti; Wurster, Siegfried; Kallatsa, Oili A.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 21 p. 6351 - 6363
反应条件
1: TEA / CH2Cl2 / 0.5 h / 0 - 20 °C
2: 86 percent / TEA; DBU / CH2Cl2 / 70 h
3: 125 mg / hydrazine hydrate / Pd/C / Heating
View Scheme
参考文献
Hoeglund, Iisa P. J.; Silver, Satu; Engstroem, Mia T.; Salo, Harri; Tauber, Andrei; Kyyroenen, Hanna-Kaisa; Saarenketo, Pauli; Hoffren, Anna-Marja; Kokko, Kurt; Pohjanoksa, Katariina; Sallinen, Jukka; Savola, Juha-Matti; Wurster, Siegfried; Kallatsa, Oili A.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 21 p. 6351 - 6363
反应条件
1: TEA / CH2Cl2 / 0.5 h / 0 - 20 °C
2: 108 mg / TEA; DBU / CH2Cl2 / 70 h
View Scheme
参考文献
Hoeglund, Iisa P. J.; Silver, Satu; Engstroem, Mia T.; Salo, Harri; Tauber, Andrei; Kyyroenen, Hanna-Kaisa; Saarenketo, Pauli; Hoffren, Anna-Marja; Kokko, Kurt; Pohjanoksa, Katariina; Sallinen, Jukka; Savola, Juha-Matti; Wurster, Siegfried; Kallatsa, Oili A.
Journal of Medicinal Chemistry, 2006 , vol. 49, # 21 p. 6351 - 6363
反应条件
1: dichloromethane / 20 °C / Inert atmosphere
2: pyridine hydrochloride / N,N-dimethyl-formamide / 36 h / 40 °C / Inert atmosphere
View Scheme
参考文献
Heller, Stephen T.; Fu, Tingting; Sarpong, Richmond
Organic Letters, 2012 , vol. 14, # 8 p. 1970 - 1973
