N,N-二甲基-2-(4-甲氧基苯基)-乙酰胺合成路线 （共 11 条）
反应条件
1: 2-(4-methoxyphenyl)-acetic acid With thionyl chloride; N,N-dimethyl-formamide in dichloromethane T=28°C; 4 h; 2: dimethylammonium chloride in dichloromethane T=10°C; 0.166667 h; 3: With triethylamine in dichloromethane T=10°C; 2 h;
参考文献
SUN PHARMACEUTICAL INDUSTRIES LIMITED
Patent: WO2005/49560 A2, 2005 ;
Location in patent: Page/Page column 8 ;
反应条件
1: T=100°C; Autoclave; 2: T=95 - 245°C; P=18751.9 Torr; 0.0158333 h; Microwave irradiation; Product distribution / selectivity;
参考文献
CLARIANT FINANCE (BVI) LIMITED
Patent: US2011/137081 A1, 2011 ;
Location in patent: Page/Page column 8 ;
反应条件
potassium phosphate; hydroquinone; tri-cyclo-hexyl-phosphine; bis(dibenzylideneacetone)-palladium(0) in tetrahydrofuran T=70°C;
参考文献
Lu, Ting-Yi; Xue, Cuihua; Luo, Fen-Tair
Tetrahedron Letters, 2003 , vol. 44, # 8 p. 1587 - 1590
反应条件
tetrakis(triphenylphosphine) palladium(0) in toluene T=65°C; 0.1 h;
参考文献
Cunico, Robert F.; Pandey, Rajesh K.
Journal of Organic Chemistry, 2005 , vol. 70, # 22 p. 9048 - 9050
反应条件
tetrakis(triphenylphosphine) palladium(0) in toluene T=100°C; 0.5 h;
参考文献
Cunico, Robert F.; Pandey, Rajesh K.
Journal of Organic Chemistry, 2005 , vol. 70, # 22 p. 9048 - 9050
反应条件
Pd((1E,4E)-1,5-diphenylpenta-1,4-dien-3-one)2; potassium hexamethylsilazane; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl in 1,4-dioxane T=100°C; 4 h;
参考文献
Shaughnessy, Kevin H.; Hamann, Blake C.; Hartwig, John F.
Journal of Organic Chemistry, 1998 , vol. 63, # 19 p. 6546 - 6553
反应条件
tert.-butylhydroperoxide; Cu(ClO4)2*6H2O T=100°C; 6 h;
参考文献
Kumar, P. Santhosh; Kumar, G. Sathish; Kumar, R. Arun; Reddy, N. Veera; Rajender Reddy
European Journal of Organic Chemistry, 2013 , # 7 p. 1218 - 1222
反应条件
Pd((1E,4E)-1,5-diphenylpenta-1,4-dien-3-one)2; potassium hexamethylsilazane; 2,2'-bis-(diphenylphosphino)-1,1'- binaphthyl in 1,4-dioxane T=100°C; 4 h;
参考文献
Shaughnessy, Kevin H.; Hamann, Blake C.; Hartwig, John F.
Journal of Organic Chemistry, 1998 , vol. 63, # 19 p. 6546 - 6553
反应条件
1,1'-carbonyldiimidazole T=160 - 165°C; 0.5 h;
参考文献
Aavula, Sanjeev Kumar; Chikkulapally, Anil; Hanumanthappa; Jyothi, Indira; Vinod; Sulur, Kumar; Manjunatha; Sythana, Suresh Kumar
Journal of Chemical Research, 2013 , vol. 37, # 3 p. 155 - 159
反应条件
KNH2 in ammonia 2 h; Irradiation;
参考文献
Palacios, S. M.; Asis, S. E.; Rossi, R. A.
Bulletin de la Societe Chimique de France, 1993 , vol. 130, # 1 p. 111 - 116
