1-(5-溴-1H-吲哚-3-基)-乙酮合成路线 （共 5 条）
反应条件
metallic chloride in toluene T=0 - 20°C; 4 h;
参考文献
UNIVERSITE JOSEPH FOURIER; DENIS, Jean-Noël; JOLIVALT, Claude, Marcelle; MAURIN, Max, Maurin, Louis; BURCHAK, Olga, Nikolaevna
Patent: WO2013/14104 A1, 2013 ;
Location in patent: Page/Page column 45 ;
反应条件
potassium hydroxide in ethanol Reflux;
参考文献
Yu, Haifeng; Yu, Zhengkun
Angewandte Chemie, International Edition, 2009 , vol. 48, p. 2929 - 2933
Angewandte Chemie, 2009 , vol. 121, p. 2973 - 2977
反应条件
sodium hydroxide in water 3.5 h; Reflux;
参考文献
Venkatanarayana; Dubey, Pramod K.
Letters in Organic Chemistry, 2011 , vol. 8, # 9 p. 656 - 662
反应条件
1: 5-Bromo-1H-indole With tin(IV) chloride in dichloromethane T=20°C; 0.5 h; 2: acetic anhydride in nitromethane; dichloromethane T=20°C; 3 h; Further stages.;
参考文献
Simon, Gaelle; Couthon-Gourves, Helene; Haelters, Jean-Pierre; Corbel, Bernard; Kervarec, Nelly; Michaud, Francois; Meijer, Laurent
Journal of Heterocyclic Chemistry, 2007 , vol. 44, # 4 p. 793 - 801
反应条件
1: propionic acid anhydride / 100 °C 2: sodium hydroxide / water / 3.5 h / Reflux View Scheme
参考文献
Venkatanarayana; Dubey, Pramod K.
Letters in Organic Chemistry, 2011 , vol. 8, # 9 p. 656 - 662
