1-苯甲酰基-2-吡咯烷羧酸合成路线 （共 8 条）
反应条件
sodium hydrogencarbonate in 1,4-dioxane; water T=0 - 20°C; Shotten-Baumann reaction;
参考文献
Kaname; Mashige; Yoshifuji
Chemical and Pharmaceutical Bulletin, 2001 , vol. 49, # 5 p. 531 - 536
反应条件
1: With potassium carbonate in tetrahydrofuran; water T=5°C; 2.5 h; Inert atmosphere; 2: With hydrogenchloride in dichloromethane; water T=15°C; pH=1;
参考文献
WO2009/91561 A1, ;
Page/Page column 26 ;
反应条件
hydrogen; dicobalt octacarbonyl in tetrahydrofuran; water T=100°C; P=120 Torr; 2 h; Yields of byproduct given;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 64, # 2 p. 620 - 623
反应条件
hydrogen; dicobalt octacarbonyl in tetrahydrofuran; water T=110°C; P=91200.1 Torr; 24 h; analogous reaction of N-benzoyl-2-pyrroline (100 deg C, 2h); addition of PdCl2(PPh3)2 or CH3CONH2; Product distributionMechanism;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 64, # 2 p. 620 - 623
反应条件
air; dicyclohexyl-carbodiimide in dichloromethane 216 h; Ambient temperature;
参考文献
Kawase, Masami
Chemical and Pharmaceutical Bulletin, 1997 , vol. 45, # 8 p. 1248 - 1253
反应条件
D-glucose; corn steep liquor; fungus Beauveria bassiana ATCC 7159 in ethanol; water Hydrolysis; 72 h; Enzymatic reaction; Title compound not separated from byproducts;
参考文献
Holland, Herbert L.; Andreana, Peter R.; Salehzadeh-Asl, Reza; Van Vliet, Aaron; Ihasz, Nancy J.; Brown, Frances M.
Monatshefte fur Chemie, 2000 , vol. 131, # 6 p. 667 - 672
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
4 h; Heating;
参考文献
Kurkin; Karchava; Yurovskaya
Chemistry of Heterocyclic Compounds, 2000 , vol. 36, # 10 p. 1141 - 1148
反应条件
D-glucose; corn steep liquor; fungus Beauveria bassiana ATCC 7159 in ethanol; water
Hydrolysis; 72 h; Enzymatic reaction; Title compound not separated from byproducts;
参考文献
Holland, Herbert L.; Andreana, Peter R.; Salehzadeh-Asl, Reza; Van Vliet, Aaron; Ihasz, Nancy J.; Brown, Frances M.
Monatshefte fur Chemie, 2000 , vol. 131, # 6 p. 667 - 672
