O-苄基-L-丝氨酸甲酯盐酸盐合成路线 (共 5 条)
反应条件
thionyl chloride in dichloromethane T=0°C; 14 h;
参考文献
BOEHRINGER INGELHEIM INTERNATIONAL GMBH
Patent: WO2009/92566 A1, 2009 ;
Location in patent: Page/Page column 112-113 ;
反应条件
thionyl chloride T=20°C; 18 h;
参考文献
Lencina, Claiton Leoneti; Dassonville-Klimpt, Alexandra; Sonnet, Pascal
Tetrahedron Asymmetry, 2008 , vol. 19, # 14 p. 1689 - 1697
反应条件
hydrogenchloride 6 h; Heating;
参考文献
Tullberg, Marcus; Grotli, Morten; Luthman, Kristina
Tetrahedron, 2006 , vol. 62, # 31 p. 7484 - 7491
反应条件
methanol; acetyl chloride Inert atmosphereMicrowave irradiationHeating;
参考文献
Organic Letters, , vol. 14, # 16 p. 4246 - 4249
反应条件
1: 100 percent / Et3N / tetrahydrofuran / a) RT, 6 h, b) 50 deg C, 2 h 2: 98 percent / LiBH4 / tetrahydrofuran / 12 h / Ambient temperature View Scheme
参考文献
Avenoza; Cativiela; Corzana; Peregrina; Zurbano
Synthesis, 1997 , # 10 p. 1146 - 1150