in diethyl ether; acetone 0.0166667 h;

Versetzen der Reaktionsloesung mit Wasser;

1: 89 percent / 1.) lithium aluminium hydride / diethyl ether / 1.) reflux, 3 h, 2.) 16 h 2: phosphorus tribromide / tetrahydrofuran; benzene / 1.) 0 deg C, 2.) 20 deg C, 3.5 h 3: 61 percent / benzene / 6 h / Heating 4: 73 percent / 1.) n-butyl-lithium / tetrahydrofuran; hexane / 1.) 20 deg C, 90 min, 2.) 20 deg C, 18 h 5: 71 percent / pyridine / 22 h 6: 97 percent / H2 / 10percent palladium on carbon / ethyl acetate / 16 h / 20 °C 7: 24 percent / potassium carbonate, potassium iodide, 18-crown-6 / acetone / 22 h / Heating 8: H2 / Lindlar catalyst / ethyl acetate / 0.33 h / 20 °C 9: 40 mg / 1.25 h / 150 °C 10: 90 percent / aqueous 10percent sodium hydroxide, ethanol / 1 h / 85 °C View Scheme

1: 2,6-dimethylpyridine / dichloromethane / 0 - 20 °C 2: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / 1,4-dioxane / 16 h / 20 - 90 °C View Scheme

potassium carbonate; potassium iodide in N,N-dimethyl-formamide T=60°C; 17 h;

1: 89 percent / 1.) lithium aluminium hydride / diethyl ether / 1.) reflux, 3 h, 2.) 16 h 2: phosphorus tribromide / tetrahydrofuran; benzene / 1.) 0 deg C, 2.) 20 deg C, 3.5 h View Scheme

potassium carbonate in acetone 12 h; Reflux;

potassium carbonate

1: K2CO3 2: LiAlH4 / tetrahydrofuran View Scheme

(i) K2CO3, acetone, (ii) KOH, MeOH; Multistep reaction;