(E)-5-羟基-3-氧代-7-[3’-(4’’-氟苯基)-1’-(1’’-甲基乙基)吲哚-2’-基]-6-庚烯酸叔丁酯合成路线 （共 3 条）
反应条件
Yield given. Multistep reaction;
参考文献
Tetrahedron, , vol. 53, # 31 p. 10659 - 10670
反应条件
1: 1.) NaBH4, Et2BOMe, 2.) aq. NaHCO3, H2O2 / 1.) THF, MeOH, -78 deg C, 1.5 h, 2.) THF, MeOH, ethyl acetate, room temperature, 15 h 2: 90 percent / aq. NaOH / ethanol / 1.58 h / 25 °C View Scheme
参考文献
Tempkin, Orin; Abel, Stephan; Chen, Chung-Pin; Underwood, Russell; Prasad, Kapa; Chen, Kau-Ming; Repic, Oljan; Blacklock, Thomas J.
Tetrahedron, 1997 , vol. 53, # 31 p. 10659 - 10670
反应条件
sodium tetrahydroborate; diethyl methoxy borane; dihydrogen peroxide; sodium hydrogencarbonate 1.) THF, MeOH, -78 deg C, 1.5 h, 2.) THF, MeOH, ethyl acetate, room temperature, 15 h; Yield given. Multistep reaction;
参考文献
Tempkin, Orin; Abel, Stephan; Chen, Chung-Pin; Underwood, Russell; Prasad, Kapa; Chen, Kau-Ming; Repic, Oljan; Blacklock, Thomas J.
Tetrahedron, 1997 , vol. 53, # 31 p. 10659 - 10670
