N-Alpha-甲基-L-苯丙氨酸-甲酯盐酸盐合成路线 （共 4 条）
反应条件
hydrogenchloride in 1,4-dioxane; dichloromethane T=0 - 20°C; 1 h;
参考文献
Ryakhovsky, Vladimir V.; Ivanov, Andrey S.
Tetrahedron, 2012 , vol. 68, # 35 p. 7070 - 7076
反应条件
hydrogenchloride 12 h; Ambient temperature;
参考文献
MacDonald, Scott A.; Willson, C. Grant; Chorev, Michael; Vernacchia, Fred S.; Goodman, Murray
Journal of Medicinal Chemistry, 1980 , vol. 23, # 4 p. 413 - 420
反应条件
1.1: sodium hydride / tetrahydrofuran; mineral oil / 0.17 h / 20 °C 1.2: 10 h / 60 °C 1.3: pH 3 2.1: hydrogenchloride / 1,4-dioxane; dichloromethane / 1 h / 0 - 20 °C View Scheme
参考文献
Ryakhovsky, Vladimir V.; Ivanov, Andrey S.
Tetrahedron, 2012 , vol. 68, # 35 p. 7070 - 7076
反应条件
1: 87 percent / N-methylmorpholine, pivaloyl chloride / tetrahydrofuran 2: 6M-HCl / 24 h / 110 °C View Scheme
参考文献
Warnke, Jonathan G.; Young, Geoffrey T.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1980 , p. 2797 - 2800
