1-硝基-4-苯基乙炔苯合成路线 （共 107 条）
反应条件
triphenylphosphine; 1-n-butyl-3-methylimidazolium tetrafluoroborate; bis(η3-allyl-μ-chloropalladium(II))
T=130°C; 2 h;
参考文献
Hierso, Jean-Cyrille; Picquet, Michel; Cattey, Helene; Meunier, Philippe
Synlett, 2006 , # 18 p. 3005 - 3008
反应条件
1: iodobenzene; acetylenecarboxylic acid With 1-methyl-pyrrolidin-2-one; 1,1'-bis-(diphenylphosphino)ferrocene; tris-(dibenzylideneacetone)dipalladium(0); tetrabutyl ammonium fluoride
T=20°C; Sonogashira coupling; 12 h;
2: 1-bromo-4-nitro-benzene T=90°C; 12 h;
参考文献
Moon, Jeongju; Jeong, Miso; Nam, Hyungoog; Ju, Jinhun; Moon, Joong Ho; Jung, Hyun Min; Lee, Sunwoo
Organic Letters, 2008 , vol. 10, # 5 p. 945 - 948
反应条件
tert.-butylnitrite; trifuran-2-yl-phosphane; palladium diacetate; acetic acid in dimethyl sulfoxide
T=20 - 32°C; Sonogashira coupling; 16 h; Inert atmosphere;
参考文献
Wu, Xiao-Feng; Neumann, Helfried; Beller, Matthias
Chemical Communications, 2011 , vol. 47, # 28 p. 7959 - 7961
反应条件
C32H28BrFeIN3Pd; potassium acetate; silver(l) oxide in 1,2-dichloro-ethane
T=80°C; 24 h;
参考文献
Li, Hong-Mei; Xu, Chen; Duan, Lu-Meng; Lou, Xin-Hua; Wang, Zhi-Qiang; Li, Zhen; Fan, Yao-Ting
Transition Metal Chemistry, 2013 , vol. 38, # 3 p. 313 - 318
反应条件
palladium diacetate; dimethyl sulfoxide
T=20°C; Sonogashira Cross-Coupling; 0.0833333 h;
参考文献
Barbero, Margherita; Cadamuro, Silvano; Dughera, Stefano
European Journal of Organic Chemistry, 2014 , vol. 2014, # 3 p. 598 - 605
反应条件
palladium diacetate; dimethyl sulfoxide
T=20°C; Sonogashira Cross-Coupling; 0.0833333 h;
参考文献
Barbero, Margherita; Cadamuro, Silvano; Dughera, Stefano
European Journal of Organic Chemistry, 2014 , vol. 2014, # 3 p. 598 - 605
反应条件
potassium tert-butylate in tetrahydrofuran; tert-butyl alcohol
参考文献
Hunter,D.H.; Cram,D.J.
Journal of the American Chemical Society, 1966 , vol. 88, # 24 p. 5765 - 5776
参考文献
Bestmann, Hans Juergen; Kamberger, Werner; Roeder, Thomas; Zimmermann, Reiner
Liebigs Annales, 1996 , # 5 p. 845 - 851
反应条件
triethylamine; palladium complex immobilised on silica gel in various solvent(s)
T=70°C; Sonogashira coupling; 12 h;
参考文献
Bandini, Marco; Luque, Rafael; Budarin, Vitaly; Macquarrie, Duncan J.
Tetrahedron, 2005 , vol. 61, # 41 p. 9860 - 9868
反应条件
1: 2CuO*Cr2O3, quinoline / 220 °C
2: KOtBu / tetrahydrofuran; 2-methyl-propan-2-ol
View Scheme
参考文献
Hunter,D.H.; Cram,D.J.
Journal of the American Chemical Society, 1966 , vol. 88, # 24 p. 5765 - 5776
