1-硝基-4-苯基乙炔苯合成路线 （共 107 条）
反应条件
(4R,5R)-DIOP; palladium diacetate; copper(l) chloride in N,N-dimethyl-formamide
T=20 - 120°C; Sila-Sonogashira cross-coupling reaction;
参考文献
Nishihara, Yasushi; Inoue, Eiji; Noyori, Shintaro; Ogawa, Daisuke; Okada, Yoshiaki; Iwasaki, Masayuki; Takagi, Kentaro
Tetrahedron, 2012 , vol. 68, # 24 p. 4869 - 4881
反应条件
N-ethyl-N,N-diisopropylamine; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct in water; isopropyl alcohol
T=100°C; 0.25 h; Microwave irradiation;
参考文献
Kabalka, George W.; Naravane, Abhijit; Zhao, Li Li
Tetrahedron Letters, 2007 , vol. 48, # 40 p. 7091 - 7093
反应条件
C18H19N3O2Pd; caesium carbonate in N,N-dimethyl-formamide
T=140°C; 1 h;
参考文献
Reddy, Police Vishnuvardhan; Srinivas, Pottabathula; Annapurna, Manne; Bhargava, Suresh; Wagler, Jorg; Mirzadeh, Nedaossadat; Kantam, Mannepalli Lakshmi
Advanced Synthesis and Catalysis, 2013 , vol. 355, # 4 p. 705 - 710
反应条件
copper(l) iodide; bis(benzonitrile)palladium(II) dichloride; (benzyl)-tri-(butyl)-ammonium chloride; sodium hydroxide; [(t-Bu)3PH]BF4 in water; toluene
T=40°C; Sonogashira coupling; 22 h; Inert atmosphere;
参考文献
Bellina, Fabio; Lessi, Marco
Synlett, 2012 , vol. 23, # 5 p. 773 - 777
反应条件
sodium hydroxide; copper(l) iodide; tetra-(n-butyl)ammonium iodide; bis-triphenylphosphine-palladium(II) chloride in toluene
T=80°C; Sonogashira coupling; 24 h;
参考文献
Chow; Wan; Low; Yeung
Journal of Organic Chemistry, 2001 , vol. 66, # 5 p. 1910 - 1913
反应条件
potassium fluoride; 1,4-dicyclohexyl-diazabutadiene; bis(dibenzylideneacetone)-palladium(0) in 1,4-dioxane
T=100°C; Stille cross-coupling reaction; 16 h;
参考文献
Li, Jin-Heng; Liang, Yun; Xie, Ye-Xiang
Tetrahedron, 2005 , vol. 61, # 30 p. 7289 - 7293
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; tetra-(n-butyl)ammonium iodide; diethylamine in acetonitrile
T=20°C; Sonogashira coupling; 1.5 h; Inert atmosphere;
参考文献
Fabrizi, Giancarlo; Goggiamani, Antonella; Sferrazza, Alessio; Cacchi, Sandro
Angewandte Chemie - International Edition, 2010 , vol. 49, # 24 p. 4067 - 4070
反应条件
copper(l) iodide; tetrakis(triphenylphosphine) palladium(0) in N,N-dimethyl-formamide
T=60°C; Substitution; 15 h;
参考文献
Chang Ho Oh; Seung Hyun Jung
Tetrahedron Letters, 2000 , vol. 41, # 44 p. 8513 - 8516
反应条件
(4-nitrophenyl)Pd(P(C6H5)3)2I in 1,2-dichloro-ethane
T=120 - 130°C; 1.5 h;
参考文献
Kashin, N. A.; Bumagina, I. G.; Bumagin, N. A.; Beletskaya, I. P.
Journal of Organic Chemistry USSR (English Translation), 1981 , vol. 17, # 1 p. 18 - 24
Zhurnal Organicheskoi Khimii, 1981 , vol. 17, # 1 p. 21 - 28
反应条件
bis-triphenylphosphine-palladium(II) chloride; diethylamine
T=55°C; 24 h;
参考文献
Kakusawa, Naoki; Kurita, Jyoji
Chemical and Pharmaceutical Bulletin, 2005 , vol. 53, # 10 p. 1369 - 1371
