3-(氯甲基)-2,4-二甲基吡啶合成路线 （共 3 条）
反应条件
thionyl chloride in dichloromethane 4 h; Ambient temperature;
参考文献
JAPAN TOBACCO INC.
Patent: WO2006/126695 A1, 2006 ;
Location in patent: Page/Page column 259 ;
反应条件
thionyl chloride in chloroform
参考文献
Japan Tobacco Inc.
Patent: US2007/32529 A1, 2007 ;
US 20070032529 A1
反应条件
1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 0 - 20 °C 2: thionyl chloride / dichloromethane / 0.5 h / 0 °C View Scheme
参考文献
TEMPERO PHARMACEUTICALS, INC.; BALOGLU, Erkan; GHOSH, Shomir; LOBERA, Mercedes; SCHMIDT, Darby, R.
Patent: WO2013/19621 A1, 2013 ;
WO 2013/019621 A1
