4-(2-甲基-4-硝基苯基)哌嗪-1-羧酸叔丁酯合成路线 （共 2 条）
反应条件
potassium carbonate in acetonitrile 48 h; Reflux;
参考文献
ABBOTT LABORATORIES; ABBOTT LABORATORIES TRADING (SHANGHAI) COMPANY, LTD.; VASUDEVAN, Anil; PENNING, Thomas Dale; CHEN, Huanming; LIANG, Bo; WANG, Shaohui; WU, Fengchun; SHEN, Yan; LIU, Cuihua; ZOU, Zhenguang
Patent: WO2012/97684 A1, 2012 ;
Location in patent: Page/Page column 97 ;
WO 2012/097684 A1
反应条件
1: With hydrogenchloride; acetic acid T=20°C; 2 h; 2: With sodium hydroxide in water 1 h;
参考文献
Molecules, , vol. 14, # 10 p. 4120 - 4135
