3-甲氧基-4-硝基吡啶-n-氧化物合成路线 （共 8 条）
反应条件
sulfuric acid; nitric acid; nitrogen(IV) oxide
参考文献
Swindell, Charles S.; Duffy, Ruth H.
Heterocycles, 1986 , vol. 24, # 12 p. 3373 - 3377
反应条件
sodium hydroxide; nitric acid in methanol
参考文献
C.D. Searle and Co.
Patent: US5652363 A1, 1997 ;
反应条件
1: 65 percent 2: 85 percent / HNO3, NO2, H2SO4 View Scheme
参考文献
Swindell, Charles S.; Duffy, Ruth H.
Heterocycles, 1986 , vol. 24, # 12 p. 3373 - 3377
反应条件
1: chloroform 2: sulfuric acid; nitric acid / 75 °C View Scheme
参考文献
den Hertog; van Ammers
Recueil des Travaux Chimiques des Pays-Bas, 1955 , vol. 74, p. 1160,1164
反应条件
hydrogen; nickel in methanol T=40°C; P=30400 Torr; 3 h;
参考文献
Wu, Zong-Quan; Jiang, Xi-Kui; Li, Zhan-Ting
Tetrahedron Letters, 2005 , vol. 46, # 46 p. 8067 - 8070
反应条件
nickel monoaluminide in methanol
参考文献
C.D. Searle and Co.
Patent: US5652363 A1, 1997 ;
反应条件
1: 77 percent / CH3COBr 2: 80 percent / Fe, HOAc View Scheme
参考文献
ISHIHARA SANGYO KAISHA, LTD.; KIRIYAMA, Kazuhisa; MATSUMOTO, Masahiro; YOSHIDA, Kotaro; BOLDBAATAR, DamdinSuren; JUKUROGI, Tatsuya; UMEMOTO, Nao; KANI, Tatsuya; MATSUDA, Yoko; TANAKA, Kumiko; KANUMA, Michiko; SHIMADA, Tatsuya
Patent: WO2014/98259 A1, 2014 ;
Location in patent: Page/Page column 40 ;
反应条件
1: 55 percent / H2 / Raney Ni / methanol / 2.5 h / 40 °C / 30400 Torr 2: 37 percent / conc. H2SO4, HNO3 / 3 h / 0 - 60 °C View Scheme
参考文献
Barraclough; Black; Cambridge; Collard; Firmin; Gerskowitch; Glen; Giles; Hill; Hull; Iyer; King; Kneen; Lindon; Nobbs; Randall; Shah; Smith; Vine; et al.
Journal of Medicinal Chemistry, 1990 , vol. 33, # 8 p. 2231 - 2239
