3-(4-甲氧基苯基)丙酸合成路线 （共 94 条）
反应条件
palladium 10 on activated carbon; hydrogen in tetrahydrofuran T=20°C; 5 h;
参考文献
Zhao, Wei; Sun, Jie; Xiang, Hua; Zeng, Yan-Yan; Li, Xiao-Bo; Xiao, Hong; Chen, De-Ying; Ma, Ren-Ling
Bioorganic and Medicinal Chemistry, 2011 , vol. 19, # 10 p. 3192 - 3203
反应条件
potassium hydroxide; water in methanol T=25°C; 2 h;
参考文献
Heffner; Joullie
Synthetic Communications, 1991 , vol. 21, # 21 p. 2231 - 2256
反应条件
potassium hydroxide; polyethylene glycol (PEG-400); potassium cyanide; nickel cyanide; cobalt(II) chloride in toluene T=90°C; P=760 Torr; 24 h;
参考文献
Tetrahedron Letters, , vol. 32, # 15 p. 1769 - 1770
反应条件
1: With sodium acetate in N,N-dimethyl acetamide T=120°C; Heck reaction; Inert atmosphere; 2: With hydrogen in N,N-dimethyl acetamide T=20 - 120°C; P=760.051 Torr;
参考文献
Advanced Synthesis and Catalysis, , vol. 350, # 16 p. 2544 - 2550
反应条件
1: With trimethylsilyl cyanide; 1,8-diazabicyclo[5.4.0]undec-7-ene in acetonitrile T=25°C; 4 h; 2: With hydrogenchloride in diethyl ether; water T=20°C; 3 h;
参考文献
Kawabata, Hirotoshi; Hayashi, Masahiko
Tetrahedron Letters, 2002 , vol. 43, # 32 p. 5645 - 5647
反应条件
hydrogen; acetic acid; palladium on activated charcoal in methanol P=2327.2 Torr; 1 h;
参考文献
Heffner; Joullie
Synthetic Communications, 1991 , vol. 21, # 21 p. 2231 - 2256
反应条件
samarium diiodide in tetrahydrofuran T=40°C; 8 h;
参考文献
Pearson, Anthony J.; Lee, Kieseung
Journal of Organic Chemistry, 1994 , vol. 59, # 8 p. 2257 - 2260
反应条件
1: With potassium carbonate; Pd-Tedicyp catalyst in N,N-dimethyl-formamide T=110°C; Heck reaction; 20 h; 2: With sodium hydroxide; water in N,N-dimethyl-formamide T=50 - 80°C;
参考文献
Lemhadri, Mhamed; Doucet, Henri; Santelli, Maurice
Tetrahedron, 2004 , vol. 60, # 50 p. 11533 - 11540
反应条件
1: in tetrahydrofuran T=20°C; P=3000.3 Torr; gas-liquid flow reactor assembly; 2: With polymer-supported sulfonic acid in tetrahydrofuran
参考文献
Polyzos, Anastasios; O'Brien, Matthew; Petersen, Trine P.; Baxendale, Ian R.; Ley, Steven V.
Angewandte Chemie - International Edition, 2011 , vol. 50, # 5 p. 1190 - 1193
反应条件
carbon monoxide; palladium on activated charcoal; 1,4-di(diphenylphosphino)-butane in ethylene glycol dimethyl ether T=150°C; P=5168 Torr; 24 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 58, # 17 p. 4739 - 4741
