3-对甲苯-1H-吡唑-5-羧酸甲酯合成路线 （共 3 条）
反应条件
sulfuric acid 16 h; Heating / reflux;
参考文献
AC IMMUNE SA
Patent: WO2008/61795 A2, 2008 ;
Location in patent: Page/Page column 49-50 ;
WO 2008/061795 A2
反应条件
1: sodium methylate / tetrahydrofuran / 8 h / 20 °C 2: acetic acid; hydrazine hydrate / 1 h / |Reflux View Scheme
参考文献
Kamal, Ahmed; Tamboli, Jaki R.; Vishnuvardhan; Adil; Nayak, V. Lakshma; Ramakrishna
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 1 p. 273 - 280
反应条件
hydrazine hydrate; acetic acid 1 h; Reflux;
参考文献
Kamal, Ahmed; Tamboli, Jaki R.; Vishnuvardhan; Adil; Nayak, V. Lakshma; Ramakrishna
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 1 p. 273 - 280
