AC-ALA-ALA-OH合成路线 （共 6 条）
反应条件
chloroformic acid ethyl ester; triethylamine in tetrahydrofuran; N,N-dimethyl-formamide 1.) -10 deg C, pH 7.5, 1 h; 2.) 4 deg C, overnight;
参考文献
Jahreis, Guenther; Fittkau, Siegfried
Journal fuer Praktische Chemie (Leipzig), 1984 , vol. 326, # 1 p. 35 - 40
反应条件
sodium hydrogencarbonate
Acetylation; 2 h;
参考文献
Cox, Russell J.; Jenkins, Helen; Schouten, James A.; Stentiford, Rosie A.; Wareing, Katrina J.
Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 13 p. 2023 - 2036
反应条件
1: 100 percent / 2 N HCl, H2 / Pd / methanol
2: 90 percent / pyridine / 3 h / Ambient temperature
3: 55 °C / thermitase, H2O, pH 8.0
View Scheme
参考文献
Jahreis, Guenther; Fittkau, Siegfried
Journal fuer Praktische Chemie (Leipzig), 1984 , vol. 326, # 1 p. 35 - 40
反应条件
1: HCl, i-amylnitrite / tetrahydrofuran; dimethylformamide / 0.25 h / -15 °C
2: NEt3 / tetrahydrofuran; dimethylformamide / 1 h / 15 °C
3: 55 °C / thermitase, H2O, pH 8.0
View Scheme
参考文献
Jahreis, Guenther; Fittkau, Siegfried
Journal fuer Praktische Chemie (Leipzig), 1984 , vol. 326, # 1 p. 35 - 40
反应条件
1: 90 percent / pyridine / 3 h / Ambient temperature
2: 55 °C / thermitase, H2O, pH 8.0
View Scheme
参考文献
Jahreis, Guenther; Fittkau, Siegfried
Journal fuer Praktische Chemie (Leipzig), 1984 , vol. 326, # 1 p. 35 - 40
反应条件
4-(N,N-dimethlyamino)pyridine; sodium hydroxide in pyridine
Ambient temperature;
参考文献
Jahreis, Guenther; Smalla, Kornelia; Fittkau, Siegfried
Journal fuer Praktische Chemie (Leipzig), 1984 , vol. 326, # 1 p. 41 - 47
