(4-氯苯基)(吗啉)甲酮合成路线 （共 19 条）
反应条件
tetrahydroxydiboron; chloro(2-dicyclohexylphosphino-2',4',6'-triisoporpyl-1,1'-biphenyl)[2-(2'-amino-1,1'-biphenyl)] palladium (II); potassium acetate; 2-(dicyclohexylphosphino)-2',4',6'-tri-i-propyl-1,1’-biphenyl in ethanol T=80°C; 1.5 h; Inert atmosphere;
参考文献
Molander, Gary A.; Cavalcanti, Livia N.; Garcia-Garcia, Carolina
Journal of Organic Chemistry, 2013 , vol. 78, # 13 p. 6427 - 6439
反应条件
Yield given. Multistep reaction;
参考文献
Massa; Ragno; Porretta; Mai; Retico; Artico; Simonetti
Archiv der Pharmazie, 1993 , vol. 326, # 9 p. 539 - 546
反应条件
1.9 mol Au/HT; potassium tert-butylate in o-xylene
T=80°C; 36 h; Inert atmosphere;
参考文献
Zhu, Jiangling; Zhang, Yan; Shi, Feng; Deng, Youquan
Tetrahedron Letters, 2012 , vol. 53, # 25 p. 3178 - 3180
反应条件
4-(N,N-dimethlyamino)pyridine; palladium diacetate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in 1,4-dioxane
T=90°C; 0.333333 h; Sealed tubeMicrowave irradiation;
参考文献
Baburajan, Poongavanam; Elango, Kuppanagounder P.
Tetrahedron Letters, 2014 , vol. 55, # 5 p. 1006 - 1010
反应条件
4-(N,N-dimethlyamino)pyridine; palladium diacetate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene in 1,4-dioxane
T=90°C; 0.333333 h; Sealed tubeMicrowave irradiation;
参考文献
Baburajan, Poongavanam; Elango, Kuppanagounder P.
Tetrahedron Letters, 2014 , vol. 55, # 5 p. 1006 - 1010
反应条件
potassium carbonate
T=120°C; 8 h;
参考文献
Dang, Tuan T.; Zhu, Yinghuai; Ghosh, Subhash C.; Chen, Anqi; Chai, Christina L. L.; Seayad, Abdul M.
Chemical Communications, 2012 , vol. 48, # 12 p. 1805 - 1807
反应条件
potassium carbonate; bis[2-(diphenylphosphino)phenyl] ether in toluene
T=105°C; P=3000.3 Torr; 12 h;
参考文献
Dang, Tuan T.; Zhu, Yinghuai; Ngiam, Joyce S. Y.; Ghosh, Subhash C.; Chen, Anqi; Seayad, Abdul M.
ACS Catalysis, 2013 , vol. 3, # 6 p. 1406 - 1410
反应条件
1: 2-chloro-5-carboxybenzene With iodine; triethylamine; phosphorous acid trimethyl ester in dichloromethane
0.166667 h; Cooling with iceInert atmosphere;
2: morpholine in dichloromethane
T=20°C; 1.5 h; Inert atmosphereCooling with ice;
参考文献
Luo, Qun-Li; Lv, Lina; Li, Yu; Tan, Jian-Ping; Nan, Wenhui; Hui, Qun
European Journal of Organic Chemistry, 2011 , # 34 p. 6916 - 6922
反应条件
tert.-butylhydroperoxide in acetonitrile
T=80°C; 5 h;
参考文献
Ekoue-Kovi, Kekeli; Wolf, Christian
Organic Letters, 2007 , vol. 9, # 17 p. 3429 - 3432
反应条件
dichlorophenyl phosphine oxide in acetonitrile
T=-4°C; 3 h;
参考文献
Kim, Yong Hae; Lim, Sang Chul; Chang, Hae Sung
Journal of the Chemical Society, Chemical Communications, 1990 , # 1 p. 36 - 37
