2-氨基-5-氯-N-甲基苯甲酰胺合成路线 （共 2 条）
反应条件
in tetrahydrofuran; water T=20°C; 1 h;
参考文献
PFIZER LIMITED; PFIZER INC.
Patent: WO2004/74291 A1, 2004 ;
Location in patent: Page 89 ;
反应条件
1: 2-amino-5-chloro-benzoic acid With 1,1'-carbonyldiimidazole in tetrahydrofuran T=20°C; Inert atmosphere; 2: methylamine in tetrahydrofuran 3 h;
参考文献
Morgentin, Remy; Barlaam, Bernard; Foote, Kevin; Hassall, Lorraine; Hawkins, Janet; Jones, Clifford D.; Le Griffon, Antoine; Peru, Aurelien; Ple, Patrick
Synthetic Communications, 2012 , vol. 42, # 1 p. 8 - 24
