1,2-二氢-3,3-二甲基-2-氧代-3H-吲哚合成路线 （共 72 条）
反应条件
1: 53 percent / NaH / dimethylformamide / 1.) 0 deg C, 10 min, 2.) RT, 1.75 h 2: 1.) LDA / 1.) THF, hexane, -78 deg C, 1.5 h, 2.) THF, hexane, a) -78 deg C, 15 min, b) from -78 deg C to RT, 2h, c) RT, overnight 3: 1.) n-BuLi, 2.) Mg, 1,2-dibromoethane 4: 40 percent / acetonitrile / 2.75 h / Irradiation View Scheme
参考文献
Heterocycles, , vol. 37, # 3 p. 1913 - 1932
反应条件
1: 1.) n-BuLi, 2.) Mg, 1,2-dibromoethane 2: 40 percent / acetonitrile / 2.75 h / Irradiation View Scheme
参考文献
Heterocycles, , vol. 37, # 3 p. 1913 - 1932
反应条件
1: 1.) LDA / 1.) THF, hexane, -78 deg C, 1.5 h, 2.) THF, hexane, a) -78 deg C, 15 min, b) from -78 deg C to RT, 2h, c) RT, overnight 2: 1.) n-BuLi, 2.) Mg, 1,2-dibromoethane 3: 40 percent / acetonitrile / 2.75 h / Irradiation View Scheme
参考文献
Heterocycles, , vol. 37, # 3 p. 1913 - 1932
反应条件
1: 81 percent / NaH / tetrahydrofuran / Heating 2: 70 percent Spectr. / tri-n-butylstannane, AIBN / toluene / Heating 3: 81 percent View Scheme
参考文献
Journal of the Chemical Society, Chemical Communications, , # 2 p. 115 - 116
反应条件
1: 70 percent Spectr. / tri-n-butylstannane, AIBN / toluene / Heating 2: 81 percent View Scheme
参考文献
Journal of the Chemical Society, Chemical Communications, , # 2 p. 115 - 116
反应条件
1: 90 percent / diethyl ether / 0 °C 2: 81 percent / NaH / tetrahydrofuran / Heating 3: 70 percent Spectr. / tri-n-butylstannane, AIBN / toluene / Heating 4: 81 percent View Scheme
参考文献
Journal of the Chemical Society, Chemical Communications, , # 2 p. 115 - 116
参考文献
Jones, Keith; Thompson, Mervyn; Wright, Colin
Journal of the Chemical Society, Chemical Communications, 1986 , # 2 p. 115 - 116
反应条件
1: dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II) dichloromethane adduct; caesium carbonate / tetrahydrofuran; water / 16 h / |Reflux 2: tri-ruthenium(0)dodecacarbonyl / chlorobenzene; N,N-dimethyl acetamide / 20 - 120 °C / |Sealed tube View Scheme
参考文献
Journal of the American Chemical Society, , vol. 136, # 3 p. 1125 - 1131
反应条件
potassium hydroxide; ethanol
参考文献
Bol.Inst.Quim.Univ.Mexico, , vol. 10, p. 3
反应条件
sulfuric acid in water Heatinghydrolysis; overnight;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 1700 - 1705
