1,2-二氢-3,3-二甲基-2-氧代-3H-吲哚合成路线 (共 72 条)
反应条件
1: 53 percent / triphenylphosphine; diethyl azodicarboxylate / dioxane / 18 h / 20 °C 2: sodium borohydride / Pd/C / methanol; H2O View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 11, # 18 p. 3889 - 3899
反应条件
methyllithium; calcium carbonate T=170 - 200°C;
参考文献
Monatshefte fuer Chemie, , vol. 18, p. 115,116
Monatshefte fuer Chemie, , vol. 16, p. 864
反应条件
1: 93 percent / aqueous sodium hydroxide / methanol / 6 h / Heating 2: 53 percent / triphenylphosphine; diethyl azodicarboxylate / dioxane / 18 h / 20 °C 3: sodium borohydride / Pd/C / methanol; H2O View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 11, # 18 p. 3889 - 3899
反应条件
1: 81 percent / DIEA 2: HOAc; H2 / PtO2 / methanol / 0.5 h View Scheme
参考文献
Tetrahedron Letters, , vol. 43, # 26 p. 4589 - 4592
反应条件
1: 33 percent / pyridine / 0.5 h / Heating 2: 65 percent / PPh3, sodium formate, Et4NCl / Pd(OAc)2 / acetonitrile / 24 h / 80 °C / other alkenes and dienes View Scheme
参考文献
Tetrahedron, , vol. 48, # 34 p. 7297 - 7320
反应条件
10 Au/Co3O4; hydrogen in n-heptane T=90°C; P=33753.4 Torr; 24 h; Autoclave; ConcentrationPressureTemperature;
参考文献
Catalysis Science and Technology, , vol. 3, # 11 p. 3000 - 3006
反应条件
sodium tetrahydroborate; palladium on activated charcoal in methanol; water
参考文献
Bioorganic and Medicinal Chemistry, , vol. 11, # 18 p. 3889 - 3899
反应条件
tri-ruthenium(0)dodecacarbonyl; tetra-(n-butyl)ammonium iodide in dimethyl sulfoxide; toluene T=20 - 120°C; 20.08 h; Sealed tube; Overall yield = 70 percentSpectr.; regioselective reaction;
参考文献
Journal of the American Chemical Society, , vol. 136, # 3 p. 1125 - 1131
反应条件
in acetonitrile 2.75 h; Irradiation;
参考文献
Johnson, A. Peter; Dutton, Jonathan K.; Pleynet, David P. M.
Heterocycles, 1994 , vol. 37, # 3 p. 1913 - 1932
参考文献
Monatshefte fuer Chemie, , vol. 18, p. 533