1,2,3,4-四氢-1-萘甲酸合成路线 (共 36 条)
反应条件
hydrogenchloride; acetic acid; tin(ll) chloride Heating;
参考文献
Belletire, J. L.; Howard, H.; Donahue, K.
Synthetic Communications, 1982 , vol. 12, # 10 p. 763 - 770
反应条件
1: n-BuLi; PhLi / diethyl ether; hexane / 2 h / 0 °C 2: 1.47 g / aq. HCOOH / 10 h / 20 °C 3: 85 percent / Jones reagent / acetone / 0.08 h / 0 °C View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 12, # 4 p. 669 - 675
反应条件
1: 1.47 g / aq. HCOOH / 10 h / 20 °C 2: 85 percent / Jones reagent / acetone / 0.08 h / 0 °C View Scheme
参考文献
Tetrahedron Asymmetry, , vol. 12, # 4 p. 669 - 675
反应条件
1: 67 percent / Et2O*BF3, Pb(OAc)4 / benzene / 15 h / Ambient temperature 2: 2 N NaOH / 2 h / Heating View Scheme
参考文献
Synthesis, , # 9 p. 845 - 846
反应条件
1: 91 percent / SOCl2 / CHCl3 / 1 h / 60 °C 2: 79 percent / 18-crown-6 / acetonitrile / 5 h / Heating 3: 30percent aq. NaOH / methanol / 12 h / Heating View Scheme
参考文献
Archiv der Pharmazie, , vol. 322, # 12 p. 889 - 892
反应条件
1: 79 percent / 18-crown-6 / acetonitrile / 5 h / Heating 2: 30percent aq. NaOH / methanol / 12 h / Heating View Scheme
参考文献
Archiv der Pharmazie, , vol. 322, # 12 p. 889 - 892
反应条件
1: NaOH / methanol / Heating 2: Raney-Ni, aq. NaOH View Scheme
参考文献
Chemische Berichte, , vol. 95, p. 2852 - 2860
反应条件
1: palladium 10 on activated carbon; hydrogen / ethyl acetate / 20 °C 2: sodium chlorite; sodium dihydrogen phosphate dihydrate; n-pent-1-ene / tetrahydrofuran; water; tert-butyl alcohol / 0 °C View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 22, # 13 p. 4259 - 4262
反应条件
hydrogenchloride; amalgamated zinc
参考文献
Arkiv foer Kemi, , vol. 12, p. 161,165
反应条件
sodium hydroxide 2 h; Heating;
参考文献
Synthesis, , # 9 p. 845 - 846