1-(2-丙炔基)环己烷-1-醇合成路线 （共 25 条）
反应条件
toluene; trimethylamine Behandeln einer Loesung des Reaktionsprodukts in Toluol mit wss. Ammoniak;
参考文献
Laeuger et al.
Helvetica Chimica Acta, 1959 , vol. 42, p. 2379,2388
反应条件
1: With zinc/copper couple
T=-16 - -14°C; Barbier type reaction; 0.75 h; Neat (no solvent);
2: With ammonium chloride
regioselective reaction;
参考文献
Ma, Xiaofang; Wang, Jin-Xian; Li, Shunxi; Wang, Ke-Hu; Huang, Danfeng
Tetrahedron, 2009 , vol. 65, # 42 p. 8683 - 8689
反应条件
in diethyl ether
T=-30 - 20°C; 1 h;
参考文献
Shu, Chao; Liu, Meng-Qi; Sun, Yu-Zhe; Ye, Long-Wu
Organic Letters, 2012 , vol. 14, # 18 p. 4958 - 4961,4
Title/Abstract Full Text Show Details
Shu, Chao; Liu, Meng-Qi; Sun, Yu-Zhe; Ye, Long-Wu
Organic Letters, 2012 , vol. 14, # 18 p. 4958 - 4961
反应条件
in tetrahydrofuran; diethyl ether
T=20°C; 1 h;
参考文献
Maddess, Matthew L.; Lautens, Mark
Organic Letters, 2005 , vol. 7, # 16 p. 3557 - 3560
反应条件
potassium hydroxide in N,N-dimethyl-formamide
参考文献
Sumitomo Chemical Company, Limited
Patent: US5258529 A1, 1993 ;
反应条件
hydrogenchloride in water; cyclohexanone
参考文献
Miles Laboratories, Inc.
Patent: US4132738 A1, 1979 ;
反应条件
1,2-di-iodoethane; zinc in tetrahydrofuran
Barbier-type reaction; 2.5 h; sonochemical reaction;
参考文献
Lee, Adam Shih-Yuan; Chu, Shu-Fang; Chang, Yu-Ting; Wang, Shu-Huei
Tetrahedron Letters, 2004 , vol. 45, # 7 p. 1551 - 1553
反应条件
titanium tetrachloride in dichloromethane
T=-78°C; Yield given;
参考文献
Haruta, Jun-ichi; Nishi, Koichi; Matsuda, Satoshi; Akai, Shuji; Tamura, Yasumitsu; Kita, Yasuyuki
Journal of Organic Chemistry, 1990 , vol. 55, # 16 p. 4853 - 4859
反应条件
titanium tetrachloride in dichloromethane
T=-78°C; 1 h; Yield given. Title compound not separated from byproducts;
参考文献
Danheiser, Rick L.; Carini, David J.
Journal of Organic Chemistry, 1980 , vol. 45, # 19 p. 3925 - 3927
反应条件
indium in tetrahydrofuran; water
T=20°C; 46 h; Title compound not separated from byproducts;
参考文献
Kwon, Jin Sun; Pae, Ae Nim; Choi, Kyung Il; Koh, Hun Yeong; Kim, Youseung; Cho, Yong Seo
Tetrahedron Letters, 2001 , vol. 42, # 10 p. 1957 - 1959
