反应条件
1: 1.) dibutylin oxide hemihydrate, 2.) Br2 / 1.) MeOH, reflux, 1.5 h, 2.) CH2Cl2, 0 deg C, 10 min 2: 70 percent / Dowex 50W-X8 / H2O / 36 h / 25 °C 3: HOAc, NaBH3CN / methanol / 1.) -78 deg C, 2 h, 2.) r.t., 20 h 4: 99 percent / H2 / 20percent Pd(OH)2/C / methanol / 24 h / 3102.9 Torr View Scheme
参考文献
Journal of Organic Chemistry, , vol. 59, # 11 p. 3175 - 3185
