4-苯基噻唑啉-2-硫酮合成路线 （共 11 条）
反应条件
sodium hydroxide in water 1 h; Heating;
参考文献
Brunet, Ernesto; Carreno, M. Carmen; Ruano, Jose Luis Garcia
Heterocycles, 1985 , vol. 23, # 5 p. 1181 - 1195
反应条件
sodium tetrahydroborate in tetrahydrofuran 2 h; Heating;
参考文献
Brunet, Ernesto; Carreno, M. Carmen; Ruano, Jose Luis Garcia
Heterocycles, 1985 , vol. 23, # 5 p. 1181 - 1195
反应条件
1: 99 percent / acetone / 2 h / Ambient temperature 2: 51 percent / sodium hydroxide / H2O / 1 h / Heating View Scheme
参考文献
Brunet, Ernesto; Carreno, M. Carmen; Ruano, Jose Luis Garcia
Heterocycles, 1985 , vol. 23, # 5 p. 1181 - 1195
反应条件
potassium hydroxide in ethanol Heating;
参考文献
Shankaran; Donnelly, Karla L.; Shah, Shrenik K.; Guthikonda, Ravindra N.; MacCoss, Malcolm; Humes, John L.; Pacholok, Stephen G.; Grant, Stephan K.; Kelly; Wong
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 17 p. 4539 - 4544
反应条件
1: H2SO4 2: aq. NaOH View Scheme
参考文献
Dewey,C.S.; Bafford,R.A.
Journal of Organic Chemistry, 1965 , vol. 30, p. 491 - 495
参考文献
Dewey,C.S.; Bafford,R.A.
Journal of Organic Chemistry, 1965 , vol. 30, p. 491 - 495
参考文献
Gabriel; Colman
Chemische Berichte, 1914 , vol. 47, p. 1870
反应条件
in ethanol 1.5 h; Heating;
参考文献
Roth,H.J.; Schlump,H.
Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft, 1963 , vol. 296, p. 213 - 217
反应条件
1: (rac)-4-phenyl-1,3-thiazolidine-2-thione With Birman's catalyst; N-ethyl-N,N-diisopropylamine in chloroform T=23°C; Resolution of racemate; 2: isobutyric anhydride With sodium sulfate in chloroform T=23°C; 4 h; Resolution of racemate; enantioselective reaction;
参考文献
Yang, Xing; Bumbu, Valentina D.; Liu, Peng; Li, Ximin; Jiang, Hui; Uffman, Eric W.; Guo, Lei; Zhang, Wei; Jiang, Xuntian; Houk; Birman, Vladimir B.
Journal of the American Chemical Society, 2012 , vol. 134, # 42 p. 17605 - 17612
反应条件
1: (rac)-4-phenyl-1,3-thiazolidine-2-thione With Birman's catalyst; N-ethyl-N,N-diisopropylamine in chloroform T=23°C; Resolution of racemate; 2: isobutyric anhydride With sodium sulfate in chloroform T=23°C; 4 h; Resolution of racemate; enantioselective reaction;
参考文献
Yang, Xing; Bumbu, Valentina D.; Liu, Peng; Li, Ximin; Jiang, Hui; Uffman, Eric W.; Guo, Lei; Zhang, Wei; Jiang, Xuntian; Houk; Birman, Vladimir B.
Journal of the American Chemical Society, 2012 , vol. 134, # 42 p. 17605 - 17612
