4-[(羟基亚胺)甲基]哌啶-1-羧酸叔丁酯合成路线 (共 3 条)
反应条件
hydroxylamine hydrochloride; sodium carbonate in methanol; water T=0 - 15°C; Cooling with ice;
参考文献
ARRAY BIOPHARMA INC.
Patent: WO2008/118718 A2, 2008 ;
Location in patent: Page/Page column 48 ;
反应条件
methanol; (ethylenediamine)Pd(NO3)2 T=60°C; Inert atmosphere;
参考文献
Tambara, Koujiro; Pantos, G. Dan
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 15 p. 2466 - 2472
反应条件
hydroxylamine hydrochloride; dimethyl sulfoxide T=70°C;
参考文献
Tambara, Koujiro; Pantos, G. Dan
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 15 p. 2466 - 2472