3-氨基-2-甲基-4(3H)喹唑啉酮合成路线 (共 61 条)
反应条件
pyridine; hydrazine hydrate 5 h; Heating;
参考文献
Kumar, Praveen; Shrivastava, Birendra; Pandeya, Surendra N.; Stables, James P.
European Journal of Medicinal Chemistry, 2011 , vol. 46, # 4 p. 1006 - 1018
反应条件
hydrazine hydrate 2 h; Reflux;
参考文献
Khan, Mahmud Tareq Hassan; Khan, Rasool; Wuxiuer, Yimingjiang; Arfan, Mohammad; Ahmed, Manzoor; Sylte, Ingebrigt
Bioorganic and Medicinal Chemistry, 2010 , vol. 18, # 12 p. 4317 - 4327
反应条件
N-hydroxy-2,4,6-trimethylbenzensulfonamide; sodium acetate in methanol T=20°C;
参考文献
Ivanov; Tsyrenov; Antonov; Lobanov; Potekhin
Chemistry of Heterocyclic Compounds, 2002 , vol. 38, # 6 p. 710 - 713
反应条件
sodium hydroxide in methanol 1 h; Heating;
参考文献
Smith; El-Hiti; Abdel-Megeed; Abdo
Journal of Organic Chemistry, 1996 , vol. 61, # 2 p. 647 - 655
反应条件
sodium hydroxide in methanol 1 h; Heating;
参考文献
Smith; El-Hiti; Abdel-Megeed; Abdo
Journal of Organic Chemistry, 1996 , vol. 61, # 2 p. 647 - 655
反应条件
hydrazine in ethanol
参考文献
Merour
Journal of Heterocyclic Chemistry, 1982 , vol. 19, # 6 p. 1425 - 1431
反应条件
1: 73 percent / 1 h / Heating 2: 76 percent / hydrazine hydrate / ethanol / 2 h / Heating View Scheme
参考文献
Biological and Pharmaceutical Bulletin, , vol. 26, # 12 p. 1711 - 1714
反应条件
1: 70.1 percent / 32 h / Heating 2: 79.1 percent / hydrazine / aq. ethanol / 0.25 h / Heating; other N-(2-carbomethoxyphenyl) imidate esters; other hydrazine deriv.; var. reaction times View Scheme
参考文献
Journal of Organic Chemistry, , vol. 50, # 16 p. 2926 - 2929
反应条件
hydrazine in ethanol 0.25 h; Heating;
参考文献
Leiby, Robert W.
Journal of Organic Chemistry, 1985 , vol. 50, # 16 p. 2926 - 2929
反应条件
1: NaOH / Heating 2: 70.1 percent / 32 h / Heating 3: 79.1 percent / hydrazine / aq. ethanol / 0.25 h / Heating; other N-(2-carbomethoxyphenyl) imidate esters; other hydrazine deriv.; var. reaction times View Scheme
参考文献
Journal of Organic Chemistry, , vol. 50, # 16 p. 2926 - 2929