5-溴-4-甲基-2-噻吩甲醛合成路线 (共 7 条)
反应条件
trichlorophosphate T=70°C; 6 h;
参考文献
Jung, Mi-Hee; Song, Kyu Ho; Ko, Kyoung Chul; Lee, Jin Yong; Lee, Hyoyoung
Journal of Materials Chemistry, 2010 , vol. 20, # 37 p. 8016 - 8020
反应条件
n-butyllithium in tetrahydrofuran; hexane; N,N-dimethyl-formamide
参考文献
Wyeth; Ligand Pharmaceuticals, Inc.
Patent: US6444668 B1, 2002 ;
反应条件
N-bromosuccinmide; acetic acid in chloroform T=20°C; 12 h;
参考文献
BIOLIPOX AB
Patent: WO2006/77412 A1, 2006 ;
Location in patent: Page/Page column 76 ;
WO 2006/077412 A1
反应条件
trichlorophosphate in N,N-dimethyl-formamide
参考文献
Wyeth; Ligand Pharmaceuticals, Inc.
Patent: US6462032 B1, 2002 ;
US 6462032 B1
反应条件
potassium carbonate in methanol
T=20 - 80°C; 0.583333 h;
参考文献
SYNTA PHARMACEUTICALS CORP.
Patent: WO2007/87429 A2, 2007 ;
Location in patent: Page/Page column 117-118 ;
反应条件
dihydrogen peroxide; aluminium trichloride in dichloromethane; water; acetonitrile
参考文献
Takeda Chemical Industries, Ltd.
Patent: US5840917 A1, 1998 ;