(3-甲氧苯甲醇)三苯基氯化膦合成路线 （共 6 条）
反应条件
in acetonitrile 12 h; Heating;
参考文献
Colabufo, Nicola Antonio; Berardi, Francesco; Perrone, Roberto; Rapposelli, Simona; Digiacomo, Maria; Balsamo, Aldo
Journal of Medicinal Chemistry, 2006 , vol. 49, # 22 p. 6607 - 6613
反应条件
1: 82 percent / SOCl2; pyridine / benzene / 1 h / Heating 2: 76 percent / benzene / 6 h / Heating View Scheme
参考文献
Journal of Chemical Research, , # 3 p. 232 - 233
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in acetonitrile 12 h; Heating / reflux;
参考文献
Berardi, Francesco; Colabufo, Nicola Antonio; Perrone, Roberto; Balsamo, Aldo; Rapposelli, Simona; Digiacomo, Maria
Patent: US2009/93493 A1, 2009 ;
Location in patent: Page/Page column 10 ;
US 20090093493 A1
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in acetonitrile Wittig reaction; 12 h; Heating;
参考文献
Colabufo, Nicola Antonio; Berardi, Francesco; Perrone, Roberto; Rapposelli, Simona; Digiacomo, Maria; Balsamo, Aldo
Journal of Medicinal Chemistry, 2006 , vol. 49, # 22 p. 6607 - 6613
反应条件
1: 3-methoxybenzyl-triphenylphosphonium chloride With 2,2,6,6-tetramethyl-piperidine; n-butyllithium in tetrahydrofuran T=-78°C; 1 h; 2: 1-Hydroxymethyl-1H-benzotriazole in tetrahydrofuran T=-78°C; Wittig olefination; 2 h;
参考文献
Deguest, Geoffrey; Bischoff, Laurent; Fruit, Corinne; Marsais, Francis
Organic Letters, 2007 , vol. 9, # 6 p. 1165 - 1167
反应条件
1: 1,8-diazabicyclo[5.4.0]undec-7-ene / acetonitrile / 12 h / Heating 2: 45 percent / H2 / Pd/C / ethanol / 12 h View Scheme
参考文献
Nesi, Giulia; Colabufo, Nicola Antonio; Contino, Marialessandra; Perrone, Maria Grazia; Digiacomo, Maria; Perrone, Roberto; Lapucci, Annalina; Macchia, Marco; Rapposelli, Simona
European Journal of Medicinal Chemistry, 2014 , vol. 76, p. 558 - 566
