3,4,5-三甲氧基苯甲腈合成路线 （共 50 条）
反应条件
in acetonitrile T=20°C; 3 h;
参考文献
Yadav, Lal Dhar S.; Srivastava, Vishnu P.; Patel, Rajesh
Tetrahedron Letters, 2009 , vol. 50, # 39 p. 5532 - 5535
反应条件
di-isopropyl azodicarboxylate; triphenylphosphine in toluene Mitsunobu dehydration; 1 h; Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 48, # 9 p. 3260 - 3268
反应条件
in acetonitrile 15 h; Heating;
参考文献
Georg, Gunda I.; Pfeifer, Sarah A.
Tetrahedron Letters, 1985 , vol. 26, # 23 p. 2739 - 2742
反应条件
in hexane T=0°C; 0.3 h; Irradiation;
参考文献
Journal of Organic Chemistry, , vol. 57, # 11 p. 3245 - 3248
反应条件
1.1: imidazole / CH2Cl2 1.2: 25 percent / methanesulfonamide; t-butyl alcohol; AD mix α / H2O / 30 h 2.1: 85 percent / hydroxylamine hydrochloride; pyridine / ethanol / 72 h / 90 °C 3.1: 30 percent / DIAD; PPh3 / toluene / 1 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 48, # 9 p. 3260 - 3268
反应条件
tetrabutylammomium bromide; copper (II) acetate monohydrate; potassium iodide in water T=180°C; 22 h;
参考文献
Ren, Yunlai; Zhao, Shuang; Tian, Xinzhe; Liu, Zhifei; Wang, Jianji; Yin, Weiping
Letters in Organic Chemistry, 2009 , vol. 6, # 7 p. 564 - 567
反应条件
potassium carbonate Elimination; methylation; 10 h; Heating;
参考文献
Kamal, Ahmed; Arifuddin; Venugopal Rao
Synthetic Communications, 1998 , vol. 28, # 24 p. 4507 - 4512
反应条件
1: 85 percent / hydroxylamine hydrochloride; pyridine / ethanol / 72 h / 90 °C 2: 30 percent / DIAD; PPh3 / toluene / 1 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 48, # 9 p. 3260 - 3268
反应条件
1: 94 percent / TEMPO; KBr; aq. sodium hypochlorite / CH2Cl2 / 0.17 h / 0 °C 2: 85 percent / hydroxylamine hydrochloride; pyridine / ethanol / 72 h / 90 °C 3: 30 percent / DIAD; PPh3 / toluene / 1 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 48, # 9 p. 3260 - 3268
反应条件
1: 97 percent / PPh3, CBr4 / Heating 2: 21 percent / hexane / 0.3 h / 0 °C / Irradiation View Scheme
参考文献
Journal of Organic Chemistry, , vol. 57, # 11 p. 3245 - 3248
