(2S,3S)-(-)-3-(4-硝基苯基)缩水甘油合成路线 （共 5 条）
反应条件
titanium(IV) isopropylate; tert.-butylhydroperoxide; L-(+)-diisopropyl tartrate in dichloromethane T=-20°C; 2 h; 4 Angstroem molecular sieves;
参考文献
Gao, Yun; Hanson, Robert M.; Klunder, Janice M.; Ko, Soo Y.; Masamune, Hiroko; Sharpless, K. Barry
Journal of the American Chemical Society, 1987 , vol. 109, # 19 p. 5765 - 5780
反应条件
lithium triethylborohydride in tetrahydrofuran T=20°C; 0.5 h; Inert atmosphere;
参考文献
Sarabia, Francisco; Vivar-Garcia, Carlos; Garcia-Castro, Miguel; Garcia-Ruiz, Cristina; Martin-Galvez, Francisca; Sanchez-Ruiz, Antonio; Chammaa, Samy
Chemistry - A European Journal, 2012 , vol. 18, # 47 p. 15190 - 15201
反应条件
sodium tetrahydroborate in methanol 0.333333 h; Title compound not separated from byproducts;
参考文献
Akagawa, Kengo; Kudo, Kazuaki
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 6 p. 843 - 847
反应条件
1: aq. H2O2; 2-[bis-(3,5-(CF3)2C6H4)](Me3SiO)C-pyrrolidine / ethanol / 16 h / 20 °C 2: NaBH4 / methanol / 0.33 h View Scheme
参考文献
Zhuang, Wei; Marigo, Mauro; Jorgensen, Karl Anker
Organic and Biomolecular Chemistry, 2005 , vol. 3, # 21 p. 3883 - 3885
反应条件
1: dihydrogen peroxide / tetrahydrofuran; water / 24 h / 0 °C 2: sodium tetrahydroborate / ethanol / 0.5 h View Scheme
参考文献
Akagawa, Kengo; Kudo, Kazuaki
Advanced Synthesis and Catalysis, 2011 , vol. 353, # 6 p. 843 - 847
