5-甲氧基-2-硝基苯甲酸合成路线 （共 47 条）
反应条件
copper in 1-methyl-pyrrolidin-2-one T=250°C; 0.25 h;
参考文献
Zhang, Yun; Jamison, Timothy F.; Patel, Sejal; Mainolfi, Nello
Organic Letters, 2011 , vol. 13, # 2 p. 280 - 283
反应条件
copper(I) oxide; bathophenanthroline in 1-methyl-pyrrolidin-2-one; quinoline T=170°C; 16 h; Product distribution;
参考文献
Goossen, Lukas J.; Thiel, Werner R.; Rodriguez, Nuria; Linder, Christophe; Melzer, Bettina
Advanced Synthesis and Catalysis, 2007 , vol. 349, # 14-15 p. 2241 - 2246
反应条件
in water pH=12; Photolysis; Quantum yieldProduct distribution; Further Variations:pH-values;
参考文献
Vialaton, Delphine; Baglio, Daniela; Paya-Perez, Ana; Richard, Claire
Pest Management Science, 2001 , vol. 57, # 4 p. 372 - 379
反应条件
1.1: 97 percent / Pd/C / ethanol / 12 h / 20 °C 2.1: 32 percent / hydrochloric acid / 12 h / 20 °C 3.1: 82 percent / pyridine / CH2Cl2 / 1 h / 20 °C 4.1: 91 percent / DIBAL / toluene / 1 h / -78 °C 5.1: 91 percent / MnO2 / benzene / 4 h / Heating 6.1: 97 percent / K2CO3 / dimethylformamide / 1 h / 80 °C 7.1: KN(TMS)2 / tetrahydrofuran / 0.25 h / -78 °C 7.2: 98 percent / tetrahydrofuran / 1 h / -78 - 20 °C 8.1: 95 percent / Cl2Ru(=CHPh)(PCy3)2 / CH2Cl2 / 1 h / 50 °C View Scheme
参考文献
Theeraladanon, Chumpol; Arisawa, Mitsuhiro; Nishida, Atsushi; Nakagawa, Masako
Tetrahedron, 2004 , vol. 60, # 13 p. 3017 - 3035
反应条件
1: diethyl ether 2: H2 / Raney nickel / methanol View Scheme
参考文献
Theeraladanon, Chumpol; Arisawa, Mitsuhiro; Nishida, Atsushi; Nakagawa, Masako
Tetrahedron, 2004 , vol. 60, # 13 p. 3017 - 3035
反应条件
1: BH3 / tetrahydrofuran / 3 h / Heating 2: pyridinium dichromate; molecular sieves / CH2Cl2 / 16 h / 20 °C View Scheme
参考文献
BIOGEN IDEC MA INC.; THOMAS, Jermaine; MI, Sha; LIN, Edward, Yin-shiang; ZHENG, Guo, Zhu; MA, Bin; CALDWELL, Richard, D.; GUCKIAN, Kevin; KUMARAVEL, Gnanasambandam
Patent: WO2012/109108 A1, 2012 ;
WO 2012/109108 A1
反应条件
1: tin (II)-chloride; aqueous hydrochloric acid View Scheme
参考文献
Tsuda et al.
Yakugaku Zasshi, 1943 , vol. 63, p. 445,447
Chem.Abstr., 1951 , p. 5156
反应条件
1: With diphenylphosphoranyl azide; triethylamine in tert-butyl alcohol 16 h; Heating / reflux; 2: With hydrogenchloride in methanol; water T=20°C; 96 h; 3: With potassium hydrogencarbonate in water 0.5 h;
参考文献
Auckland Uniservices Limited
Patent: EP1468688 A2, 2004 ;
Location in patent: Page/Page column 24; 47 ;
反应条件
1: triethylamine; trifluoroacetic anhydride / dichloromethane / 1 h / 20 °C 2: water; sodium dithionite / ethanol / 1 h / Reflux View Scheme
参考文献
KALYPSYS, INC.; BORCHARDT, Allen; DAVIS, Robert; BEAUREGARD, Clay; BECKER, Daniel; GAMACHE, Daniel; NOBLE, Stewart, A.; HELLBERG, Mark, R.; KLIMKO, Peter, G.; ZHIHAI, Qui; PAYNE, Joseph, E.; YANNI, John
Patent: WO2011/112731 A2, 2011 ;
WO 2011/112731 A2
反应条件
1: ferrosulfate; ammonia 2: Behandeln mit Kupferbromuer.Diazotization View Scheme
参考文献
Pschorr
Justus Liebigs Annalen der Chemie, 1912 , vol. 391, p. 44
