1-(2-溴氧基)-4-溴苯合成路线 （共 7 条）
反应条件
sodium hydroxide in water 11 h; Heating / reflux;
参考文献
BIOLIPOX AB
Patent: WO2005/123673 A1, 2005 ;
Location in patent: Page/Page column 76 ;
WO 2005/123673 A1
反应条件
γ-picolinium bromochromate in acetonitrile T=90°C; 0.833333 h; regioselective reaction;
参考文献
Mahmoodi; Yazdanbakhsh; Hassanzadeh
Oriental Journal of Chemistry, 2011 , vol. 27, # 2 p. 429 - 434
反应条件
carbon tetrabromide; triphenylphosphine in tetrahydrofuran T=0°C; 4 h; Inert atmosphere;
参考文献
Gegout, Aline; Delgado, Juan Luis; Nierengarten, Jean-Franois; Delavaux-Nicot, Beatrice; Listorti, Andrea; Chiorboli, Claudio; Belbakra, Abdelhalim; Armaroli, Nicola
New Journal of Chemistry, 2009 , vol. 33, # 10 p. 2174 - 2182
参考文献
Tetrahedron Letters, , vol. 21, p. 2911 - 2914
参考文献
Rindfusz; Ginnings; Harnack
Journal of the American Chemical Society, 1920 , vol. 42, p. 163
反应条件
1: 57 percent / NaH / tetrahydrofuran / Heating
2: 62 percent / aq. LiOH / 12 h / 90 °C
View Scheme
参考文献
Abraham, D. J.; Kennedy, P. E.; Mehanna, A. S.; Patwa, D. C.; Williams, F. L.
Journal of Medicinal Chemistry, 1984 , vol. 27, # 8 p. 967 - 978
反应条件
1: potassium tert-butylate / tetrahydrofuran / 0 - 20 °C
2: diethylzinc / hexane; 1,2-dichloro-ethane / 3 h / 0 °C
View Scheme
参考文献
ROTH, Gerald Juergen; FLECK, Martin; LEHMANN-LINTZ, Thorsten; NOSSE, Bernd
Patent: US2013/143876 A1, 2013 ;
Title/Abstract Full Text Show Details
FLECK, Martin; NOSSE, Bernd; HEINE, Niklas; ROTH, Gerald Juergen
Patent: US2013/158004 A1, 2013 ;
Title/Abstract Full Text Show Details
BOEHRINGER INGELHEIM INTERNATIONAL GMBH; FLECK, Martin; HEIMANN, Annekatrin; HEINE, Niklas; NOSSE, Bernd; ROTH, Gerald Juergen
Patent: WO2014/56771 A1, 2014 ;
