1-乙酰基-1H-苯并噻唑合成路线 （共 33 条）
反应条件
1: 2-methyl-3-oxobutanoic acid ethyl ester With sodium hydride in tetrahydrofuran
T=20°C; 0.666667 h;
2: PhCOBt in tetrahydrofuran
T=20°C;
参考文献
Katritzky, Alan R.; Wang, Zuoquan; Wang, Mingyi; Wilkerson, Chavon R.; Hall, C. Dennis; Akhmedov, Novruz G.
Journal of Organic Chemistry, 2004 , vol. 69, # 20 p. 6617 - 6622
反应条件
1: acetylacetone With sodium hydride in tetrahydrofuran
T=20°C; 0.666667 h;
2: PhCOBt in tetrahydrofuran
T=20°C; 14 h;
3: With hydrogenchloride in tetrahydrofuran
参考文献
Katritzky, Alan R.; Wang, Zuoquan; Wang, Mingyi; Wilkerson, Chavon R.; Hall, C. Dennis; Akhmedov, Novruz G.
Journal of Organic Chemistry, 2004 , vol. 69, # 20 p. 6617 - 6622
参考文献
Parshad; Sharma
Journal of the Indian Chemical Society, 1990 , vol. 67, # 2 p. 150 - 152
反应条件
1: 1-(N-ferrocenylmethyl)benzotriazole With n-butyllithium in tetrahydrofuran; hexane
T=20°C; Inert atmosphere;
2: acetyl chloride in tetrahydrofuran; hexane
Inert atmosphere;
3: water in thiophene; hexane
参考文献
Moiseev; Cherevatskaya; Verbitskaya; Glukhov; Peregudov; Kalinin
Russian Chemical Bulletin, 2012 , vol. 61, # 10 p. 1933 - 1942
Izv. Akad. Nauk, Ser. Khim., 2012 , # 10 p. 1918 - 1927,10
反应条件
1: 1-N-(1-ferrocenyl-1-methyl)ethylbenzotriazole With n-butyllithium in tetrahydrofuran; hexane
T=-70 - 20°C; Inert atmosphere;
2: acetyl chloride in tetrahydrofuran; hexane
Inert atmosphere;
3: water in thiophene; hexane
参考文献
Moiseev; Cherevatskaya; Verbitskaya; Glukhov; Peregudov; Kalinin
Russian Chemical Bulletin, 2012 , vol. 61, # 10 p. 1933 - 1942
Izv. Akad. Nauk, Ser. Khim., 2012 , # 10 p. 1918 - 1927,10
参考文献
Gasparini, J. P.; Gassend, R.; Maire, J. C.; Elguero, J.
Journal of Organometallic Chemistry, 1980 , vol. 188, # 2 p. 141 - 150
反应条件
1: 12 percent / benzene / 24 h / Irradiation
2: CH3COONa
View Scheme
参考文献
Parshad; Sharma
Journal of the Indian Chemical Society, 1990 , vol. 67, # 2 p. 150 - 152
反应条件
1: 26 percent / benzene / 24 h / Irradiation
2: CH3COONa
View Scheme
参考文献
Parshad; Sharma
Journal of the Indian Chemical Society, 1990 , vol. 67, # 2 p. 150 - 152
参考文献
Gaylord; Naughton
Journal of Organic Chemistry, 1957 , vol. 22, p. 1022,1023
反应条件
in tetrahydrofuran
T=55°C; 0.75 h; Inert atmosphereGreen chemistry;
参考文献
Pasqua, Adele E.; Matheson, Mhairi; Sewell, Alan L.; Marquez, Rodolfo
Organic Process Research and Development, 2011 , vol. 15, # 2 p. 467 - 470
